A Novel Reassortant H2N3 Influenza Virus Lsolated from China

LI Xiao Dan; ZOU Shu Mei; ZHANG Ye; BAI Tian; GAO Rong Bao; ZHANG Xin; WU Jie; SHU Yue Long

doi:10.3967/bes2014.047

PDF
Cite
Share

facebook

twitter

google

linkedin

Volume 27 Issue 4

Apr. 2014

Turn off MathJax

Article Contents

Article Navigation > Biomedical and Environmental Sciences > 2014 > 27(4): 240-249

LI Xiao Dan, ZOU Shu Mei, ZHANG Ye, BAI Tian, GAO Rong Bao, ZHANG Xin, WU Jie, SHU Yue Long. A Novel Reassortant H2N3 Influenza Virus Lsolated from China[J]. Biomedical and Environmental Sciences, 2014, 27(4): 240-249. doi: 10.3967/bes2014.047

Citation:

LI Xiao Dan, ZOU Shu Mei, ZHANG Ye, BAI Tian, GAO Rong Bao, ZHANG Xin, WU Jie, SHU Yue Long. A Novel Reassortant H2N3 Influenza Virus Lsolated from China[J]. Biomedical and Environmental Sciences, 2014, 27(4): 240-249. doi: 10.3967/bes2014.047

A Novel Reassortant H2N3 Influenza Virus Lsolated from China

doi: 10.3967/bes2014.047

Chinese National Influenza Center, Nationallnstitute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Key Laboratory of Surveillance and Early warning on Infectious Disease, Key Laboratory for Medical Virology, National Health and family planning Commission, Beijing 102206, China
Center, for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, Guangdong, China

Funds: This research is supported by a National Basic Research grant (973)(2011CB504704)

Abstract

Objective To analyze the genetic composition of a novel H2N3 virus isolate identified from a duck cage swab in a live poultry market (LPM) in 2009 in Guangdong province of China.
Methods PCR-positive specimens were inoculated into embryonated chicken eggs and subtyped by conventional RT-PCR. All segments of the virus A/environment/Guangdong/2/2009 were sequenced, and phylogenetic trees were constructed and analyzed.
Results The genes of this virus belong to Eurasian-lineage avian viruses. The virus is a reassortant with the HA gene from an H2N2 virus and the NA gene from an H5N3 virus. The PB1, PB2, and NP genes were from an H4N6 virus, the PA was from an H3N8 virus, the M gene was from an H1N3 virus, and the NS gene was from an H10N6 virus.
Conclusion market. Its A novel avian-origin reassortant H2N3 influenza virus was detected in a live poultry potential impacts and evolution should be closely monitored.
- Avian influenza,
- Gene analysis,
- H2N3
References
Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views(1860) PDF downloads(34) Cited by()

Proportional views

A Novel Reassortant H2N3 Influenza Virus Lsolated from China

doi: 10.3967/bes2014.047

Chinese National Influenza Center, Nationallnstitute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Key Laboratory of Surveillance and Early warning on Infectious Disease, Key Laboratory for Medical Virology, National Health and family planning Commission, Beijing 102206, China

Center, for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, Guangdong, China

Funds: This research is supported by a National Basic Research grant (973)(2011CB504704)

Key words:

Avian influenza /
Gene analysis /
H2N3

Abstract: Objective To analyze the genetic composition of a novel H2N3 virus isolate identified from a duck cage swab in a live poultry market (LPM) in 2009 in Guangdong province of China.
Methods PCR-positive specimens were inoculated into embryonated chicken eggs and subtyped by conventional RT-PCR. All segments of the virus A/environment/Guangdong/2/2009 were sequenced, and phylogenetic trees were constructed and analyzed.
Results The genes of this virus belong to Eurasian-lineage avian viruses. The virus is a reassortant with the HA gene from an H2N2 virus and the NA gene from an H5N3 virus. The PB1, PB2, and NP genes were from an H4N6 virus, the PA was from an H3N8 virus, the M gene was from an H1N3 virus, and the NS gene was from an H10N6 virus.
Conclusion market. Its A novel avian-origin reassortant H2N3 influenza virus was detected in a live poultry potential impacts and evolution should be closely monitored.

Citation: