Volume 19 Issue 6
Dec.  2006
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K.KRISHNAMURTHI, S. SARAVANA DEVI, T. CHAKRABARTI. DNA Damage Caused By Pesticide-contaminated Soil[J]. Biomedical and Environmental Sciences, 2006, 19(6): 427-431.
Citation: K.KRISHNAMURTHI, S. SARAVANA DEVI, T. CHAKRABARTI. DNA Damage Caused By Pesticide-contaminated Soil[J]. Biomedical and Environmental Sciences, 2006, 19(6): 427-431.

DNA Damage Caused By Pesticide-contaminated Soil

  • Objective To determine the DNA damaging potential and the genotoxicity of individual compounds in pesticide contaminated soil. Methods In the present study, DNA damaging potential of pesticide-contaminated soil and the genotoxicity of individual compounds present in the soil were assessed using fluorimetric analysis of DNA unwinding assay. Results The contaminated soil sample showed 79% (P<0.001) of DNA strand break, whereas technical grade of major carbaryl and α-naphthol constituents of the contaminated soil showed 64% (P<0.01) and 60% (P<0.02) damage respectively. Conclusion Our results indicate that the toxicity caused by contaminated soil is mainly due to carbaryl and α -napthol, which are the major constituents of the soil sample analyzed by GC-MS.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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DNA Damage Caused By Pesticide-contaminated Soil

Abstract: Objective To determine the DNA damaging potential and the genotoxicity of individual compounds in pesticide contaminated soil. Methods In the present study, DNA damaging potential of pesticide-contaminated soil and the genotoxicity of individual compounds present in the soil were assessed using fluorimetric analysis of DNA unwinding assay. Results The contaminated soil sample showed 79% (P<0.001) of DNA strand break, whereas technical grade of major carbaryl and α-naphthol constituents of the contaminated soil showed 64% (P<0.01) and 60% (P<0.02) damage respectively. Conclusion Our results indicate that the toxicity caused by contaminated soil is mainly due to carbaryl and α -napthol, which are the major constituents of the soil sample analyzed by GC-MS.

K.KRISHNAMURTHI, S. SARAVANA DEVI, T. CHAKRABARTI. DNA Damage Caused By Pesticide-contaminated Soil[J]. Biomedical and Environmental Sciences, 2006, 19(6): 427-431.
Citation: K.KRISHNAMURTHI, S. SARAVANA DEVI, T. CHAKRABARTI. DNA Damage Caused By Pesticide-contaminated Soil[J]. Biomedical and Environmental Sciences, 2006, 19(6): 427-431.

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