Volume 12 Issue 4
Dec.  1999
Turn off MathJax
Article Contents

R.C.AGRAWAL. Induction of Chromosomal Aberrations by Propoxur in Mouse Bone Marrow Ceils[J]. Biomedical and Environmental Sciences, 1999, 12(4): 292-295.
Citation: R.C.AGRAWAL. Induction of Chromosomal Aberrations by Propoxur in Mouse Bone Marrow Ceils[J]. Biomedical and Environmental Sciences, 1999, 12(4): 292-295.

Induction of Chromosomal Aberrations by Propoxur in Mouse Bone Marrow Ceils

  • Propoxur is a widely used dithiocarbamate insecticide. In this study, the clastogenic effect of propoxur has been evaluated using chromosomal aberration assay in mouse bone marrow cells. Singlei. p. administration of propoxur, at 25 nag/kg b.wt., a maximum tolerated dose (MTD) and 12.5mg/kg b.wt (50% of MTD) have significantly induced different types of aberrations after 24 h of treatment. The aberrations were dose and time dependent and reached a maximum after 24 h of exposure. The sresult suggest a genotoxic potential of propoxur.
  • 加载中
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(764) PDF downloads(1) Cited by()

Proportional views
Related

Induction of Chromosomal Aberrations by Propoxur in Mouse Bone Marrow Ceils

Abstract: Propoxur is a widely used dithiocarbamate insecticide. In this study, the clastogenic effect of propoxur has been evaluated using chromosomal aberration assay in mouse bone marrow cells. Singlei. p. administration of propoxur, at 25 nag/kg b.wt., a maximum tolerated dose (MTD) and 12.5mg/kg b.wt (50% of MTD) have significantly induced different types of aberrations after 24 h of treatment. The aberrations were dose and time dependent and reached a maximum after 24 h of exposure. The sresult suggest a genotoxic potential of propoxur.

R.C.AGRAWAL. Induction of Chromosomal Aberrations by Propoxur in Mouse Bone Marrow Ceils[J]. Biomedical and Environmental Sciences, 1999, 12(4): 292-295.
Citation: R.C.AGRAWAL. Induction of Chromosomal Aberrations by Propoxur in Mouse Bone Marrow Ceils[J]. Biomedical and Environmental Sciences, 1999, 12(4): 292-295.

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return