Volume 26 Issue 9
Sep.  2013
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WANG Hai Bin, SONG Yan Yan, YOU Yuan Hai, WANG Heng Wei, HAN Qin Hua, ZHAO Jian Hong, ZHANG Xiao Xi. Molecular Epidemiological Analysis of Group A Streptococci Isolated from Children in Chaoyang District of Beijing, 2011: emm Types, Virulence Factor Genes and Erythromycin Resistant Genes[J]. Biomedical and Environmental Sciences, 2013, 26(9): 782-784. doi: 10.3967/0895-3988.2013.09.012
Citation: WANG Hai Bin, SONG Yan Yan, YOU Yuan Hai, WANG Heng Wei, HAN Qin Hua, ZHAO Jian Hong, ZHANG Xiao Xi. Molecular Epidemiological Analysis of Group A Streptococci Isolated from Children in Chaoyang District of Beijing, 2011: emm Types, Virulence Factor Genes and Erythromycin Resistant Genes[J]. Biomedical and Environmental Sciences, 2013, 26(9): 782-784. doi: 10.3967/0895-3988.2013.09.012
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Molecular Epidemiological Analysis of Group A Streptococci Isolated from Children in Chaoyang District of Beijing, 2011: emm Types, Virulence Factor Genes and Erythromycin Resistant Genes

doi: 10.3967/0895-3988.2013.09.012

  • Laboratory of Microbiology, Chaoyang District Center for Disease Control and Prevention, Beijing 100021, China

  • Department of Diagnosis, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China ; State Key Laboratory for Infectious Disease Prevention and Control, Beijing 102206, China

  • Group A streptococcus (GAS) causes a wide range of diseases in the human population.GAS diseases are more common in children than in adults,with clinical manifestations ranging from pharyngitis and impetigo to invasive infections and post streptococcal sequelae,such as acute rheumatic fever and acute post-streptococcal glomerulonephritis[1].GAS harbors a host of virulence factors that contribute to its complex pathogenicity and differences in the disease severity and frequency.M protein,one of the major virulence factors,is encoded by the emm gene induces a type of specific host immune response and confers antiphagocytic properties.

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Molecular Epidemiological Analysis of Group A Streptococci Isolated from Children in Chaoyang District of Beijing, 2011: emm Types, Virulence Factor Genes and Erythromycin Resistant Genes

doi: 10.3967/0895-3988.2013.09.012
  • Laboratory of Microbiology, Chaoyang District Center for Disease Control and Prevention, Beijing 100021, China
  • Department of Diagnosis, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China ; State Key Laboratory for Infectious Disease Prevention and Control, Beijing 102206, China

Abstract: 

Group A streptococcus (GAS) causes a wide range of diseases in the human population.GAS diseases are more common in children than in adults,with clinical manifestations ranging from pharyngitis and impetigo to invasive infections and post streptococcal sequelae,such as acute rheumatic fever and acute post-streptococcal glomerulonephritis[1].GAS harbors a host of virulence factors that contribute to its complex pathogenicity and differences in the disease severity and frequency.M protein,one of the major virulence factors,is encoded by the emm gene induces a type of specific host immune response and confers antiphagocytic properties.

WANG Hai Bin, SONG Yan Yan, YOU Yuan Hai, WANG Heng Wei, HAN Qin Hua, ZHAO Jian Hong, ZHANG Xiao Xi. Molecular Epidemiological Analysis of Group A Streptococci Isolated from Children in Chaoyang District of Beijing, 2011: emm Types, Virulence Factor Genes and Erythromycin Resistant Genes[J]. Biomedical and Environmental Sciences, 2013, 26(9): 782-784. doi: 10.3967/0895-3988.2013.09.012
Citation: WANG Hai Bin, SONG Yan Yan, YOU Yuan Hai, WANG Heng Wei, HAN Qin Hua, ZHAO Jian Hong, ZHANG Xiao Xi. Molecular Epidemiological Analysis of Group A Streptococci Isolated from Children in Chaoyang District of Beijing, 2011: emm Types, Virulence Factor Genes and Erythromycin Resistant Genes[J]. Biomedical and Environmental Sciences, 2013, 26(9): 782-784. doi: 10.3967/0895-3988.2013.09.012
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