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Original Article
Burden of Cirrhosis and Other Chronic Liver Diseases Caused by Specific Etiologies in China, 1990−2016: Findings from the Global Burden of Disease Study 2016
LI Man, WANG Zhuo Qun, ZHANG Lu, ZHENG Hao, LIU Dian Wu, ZHOU Mai Geng
2020, 33(1): 1-10.   doi: 10.3967/bes2020.001
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Objective To estimate the burden of cirrhosis and other chronic liver diseases caused by specific etiologies in China. Methods Data from the Global Burden of Disease Study 2016 (GBD 2016) were used. We evaluated the burden by analyzing age-sex-province-specific prevalence, mortality, and disability-adjusted life-years (DALYs) of 33 provinces in China. Results From 1990 to 2016, prevalence cases in thousands increased by 73.7% from 6833.3 (95% UI: 6498.0–7180.6) to 11869.6 (95% UI: 11274.6–12504.7). Age-standardized mortality and DALY rates per 100,000 decreased by 51.2% and 53.3%, respectively. Male and elderly people (aged ≥ 60 years) preponderance were found for prevalence, mortality, and DALYs. The number of prevalence cases, deaths, and DALYs due to hepatitis C virus (HCV) increased by 86.6%, 8.7%, and 0.9%, respectively. Also, age-standardized prevalence rates decreased in 31 provinces, but increased in Yunnan and Shandong. The Socio-demographic Index (SDI) values were negatively correlated with age-standardized mortality and DALY rates by provinces in 2016; the correlation coefficients were −0.817 and −0.828, respectively. Conclusion Cirrhosis and other chronic liver diseases remain a huge health burden in China, with the increase of population and the aging of population. Hepatitis B virus (HBV) remains the leading cause of the health burden in China.
Effect of Body Mass Index on the Associations between Parity and Metabolic Syndrome and its Components among Northern Chinese Women
YAO Yan, LIU Hua Min, WANG Xian Wei, FENG Xia, GAO Li Jian, LI Dong, ZHOU Yong
2020, 33(1): 11-18.   doi: 10.3967/bes2020.002
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Objectives The aims of this study were to assess the associations between parity and metabolic syndrome (MetS) and its components and to evaluate the effects of body mass index (BMI) on these associations. Methods A total of 5,674 women were enrolled from Jidong and Kailuan communities (Tangshan, Hebei) in Northern China. All participants completed standardized questionnaires, physical examination, and biochemical measurements. Logistic regression analysis was used to test the associations. Results Compared with women with parity of one, nulliparous women had decreased odds ratios (ORs); those with parity of two had odds of abdominal obesity [OR = 1.45, 95% confidence interval (CI) 1.17–1.81, P < 0.001], high blood pressure (OR = 1.26, 95% CI: 1.03–1.54, P = 0.025), elevated fasting glucose levels (OR = 1.36, 95% CI: 1.03–1.79, P = 0.029), and MetS (OR = 1.39, 95% CI: 1.13–1.73, P = 0.002); and those with parity of three or more had increased odds of elevated triglyceride levels (OR = 1.42, 95% CI: 1.04–1.94, P = 0.027) and MetS (OR = 1.50, 95% CI: 1.10–2.05, P = 0.011) after complete adjustment for confounders. Furthermore, BMI and age subgroups partially modified the associations between parity and MetS and its components. Conclusions Parity is positively associated with MetS and select components in women. BMI is an important modifier involved in the associations between parity and MetS.
Association of Red Meat Usual Intake with Serum Ferritin and the Risk of Metabolic Syndrome in Chinese Adults: A Longitudinal Study from the China Health and Nutrition Survey
HUANG Li Na, WANG Hui Jun, WANG Zhi Hong, ZHANG Ji Guo, JIA Xiao Fang, ZHANG Bing, DING Gang Qiang
2020, 33(1): 19-29.   doi: 10.3967/bes2020.003
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Objective The present study aimed to investigate the association of red meat usual intake with metabolic syndrome (MetS), and explore the contribution of red meat usual intake to serum ferritin. Methods Based on the data from the longitudinal China Health and Nutrition Survey (CHNS), 2,797 healthy adults aged 18–75 years without hypertension, diabetes, and MetS were selected in 2009 as subjects and follow-up studies were carried out till 2015. We used the National Cancer Institute (NCI) method to estimate the usual intake of foods. Multivariable logistic regressions were performed to evaluate the association between red meat usual intake and the risk of MetS. Quantile regression analysis was used to study the relationship between red meat consumption and serum ferritin levels. Results After adjusting for potential confounders, red meat, and fresh red meat were positively associated with the risk of MetS (RR = 1.41, 95% CI: 1.05–1.90 and RR = 1.37, 95% CI: 1.02–1.85, respectively). These relationships showed increasing trend (P < 0.05). The level of serum ferritin increased significantly with the number of MetS components (P < 0.05). The quantile regression analysis showed that red meat and fresh red meat usual intake had a significant positive association with serum ferritin levels across the entire conditional serum ferritin distribution (P < 0.05). Processed red meat did not exhibit a similar association. Conclusion Higher red meat usual intake was associated with an increased risk of MetS and elevated serum ferritin levels.
Analysis of Preoperative Factors Influencing Hypoglossal-facial ‘Side’-to-side Neurorrhaphy for Facial Paralysis after Excision of Acoustic Neuroma
SU Di Ya, WAN Hong, LI De Zhi, QIAO Hui, SCHUMACHER Michael, LIU Song
2020, 33(1): 30-36.   doi: 10.3967/bes2020.004
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Objective Hypoglossal nerve-facial nerve ‘side’-to-side neurorrhaphy is a new method for the treatment of potential incomplete facial paralysis after acoustic neuroma. However, there are differences in postoperative outcomes among patients. This study analysed preoperative factors that may influence the treatment outcomes of neurorrhaphy. Methods We performed a retrospective study of 53 patients who were treated by neurorrhaphy for facial paralysis after acoustic neuroma resection. After a one-year follow-up period, the patients were divided into two groups according to facial functional outcome: better recovery or ordinary recovery. We analysed the following factors: gender, age, tumour size, and characteristics, tumour adhesion to the facial nerve, the duration of facial paralysis (DFP) and F wave appearance prior to neurorrhaphy (F wave). Results Univariate analysis showed significant differences between the two groups in DFP (P = 0.0002), tumour adhesion to the facial nerve (P = 0.0079) and F waves (P = 0.0048). Logistic regression analysis of these factors also showed statistical significance with P values of 0.042 for the DFP, 0.043 for F waves, and 0.031 for tumour adhesion to the facial nerve. Conclusions Tumour adhesion to the facial nerve, F waves appearance and DFP prior to neurorrhaphy are the predominant factors that influence treatment outcomes.
Effects of Incretin-based Therapies on Weight-related Indicators among Patients with Type 2 Diabetes: A Network Meta-analysis
XU Lu, YU Shu Qing, GAO Le, HUANG Yi, WU Shan Shan, YANG Jun, SUN Yi Xin, YANG Zhi Rong, CHAI San Bao, ZHANG Yuan, JI Li Nong, SUN Feng, ZHAN Si Yan
2020, 33(1): 37-47.   doi: 10.3967/bes2020.005
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Objective To evaluate the effects of incretin-based therapies on body weight as the primary outcome, as well as on body mass index (BMI) and waist circumference (WC) as secondary outcomes. Methods Databases including Medline, Embase, the Cochrane Library, and ( were searched for randomized controlled trials (RCTs). Standard pairwise meta-analysis and network meta-analysis (NMA) were both carried out. The risk of bias (ROB) tool recommended by the Cochrane handbook was used to assess the quality of studies. Subgroup analysis, sensitivity analysis, meta-regression, and quality evaluation based on the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) were also performed. Results A total of 292 trials were included in this study. Compared with placebo, dipeptidyl-peptidase IV inhibitors (DPP-4Is) increased weight slightly by 0.31 kg [95% confidence interval (CI): 0.05, 0.58] and had negligible effects on BMI and WC. Compared with placebo, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) lowered weight, BMI, and WC by −1.34 kg (95% CI: −1.60, −1.09), −1.10 kg/m2 (95% CI: −1.42, −0.78), and −1.28 cm (95% CI: −1.69, −0.86), respectively. Conclusion GLP-1 RAs were more effective than DPP-4Is in lowering the three indicators. Overall, the effects of GLP-1 RAs on weight, BMI, and WC were favorable.
Letter to the Editor
Analysis of Cardiovascular Risk Factors in Newly Defined Stage 1 Hypertension among Chinese on the Basis of the 2017 ACC/AHA Hypertension Guidelines
LIANG Kai, WANG Chuan, YAN Fei, YANG Jun Peng, TIAN Meng, WANG Ling Shu, HOU Xin Guo, CHEN Li
2020, 33(1): 48-52.   doi: 10.3967/bes2020.006
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Characteristics of Hypertension Death in Low-income Regions of Inner Mongolia, China
YU Di, DU Mao Lin, SUN De Jun, QIAO Su Fang, MA Yu Jia, Wang Li, GAO Yu Min, CHEN Yong Sheng, MENG Yong Liang, SUN Xiao Ling, GUO Wen Fang, WANG Qing Xia, ZHANG Hai Rong, LI Wu Yun Ta Na, JIA Lei, HAO Jing, ZHAO Neng Jun, SUN Juan
2020, 33(1): 53-57.   doi: 10.3967/bes2020.007
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Optimization of Gas Chromatography-electron Ionization-tandem Mass Spectrometry for Determining Toxic Non-ortho Polychlorinated Biphenyls in Breast Milk
Iva Šimić, Gordana Jovanović, Snježana Herceg Romanić, Darija Klinčić, Marijana Matek Sarić, Aleksandar Popović
2020, 33(1): 58-61.   doi: 10.3967/bes2020.008
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Strong Correlation of Abnormal Serum and Urinary Iodine Levels with Papillary Thyroid Cancer: A Case-control Study
XIU Cheng, HE Qian, ZHAO Hong Jian, YUAN Zhen Nan, GUO Lun Hua, WANG Feng Qian, YANG Xian Guang, TIAN Qiu Shi, SUN Qi Hao, MIAO Su Sheng, SUN Ji, FAN Li Jun, JIA Shen Shan
2020, 33(1): 62-67.   doi: 10.3967/bes2020.009
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Contamination of Prohibited Substances in Various Food Products in Guangzhou, China
MHUNGU Florence, HU Ke Qi, ZHANG Wei Wei, ZHOU Zhi Feng, SHI Ming, LIU Yun Gang
2020, 33(1): 68-71.   doi: 10.3967/bes2020.010
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Seroprevalence of Bartonella henselae and Identification of Risk Factors in China
SONG Xiu Ping, ZHANG Hai Bin, LIU Qi Yong, SUN Ji Min, XU Lei, GU Shao Hua, SUN Wan Wan, YUE Yu Juan, REN Dong Sheng, WANG Jun, LI Dong Mei
2020, 33(1): 72-75.   doi: 10.3967/bes2020.011
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Serum samples were tested for Bartonella henselae IgG antibodies using indirect immunofluorescence assays. We then analyzed associated risk factors. Serum samples were considered positive when reactive at a dilution of more than 1:320. Differences between groups and risk factors associated with Bartonella exposure were statistically analyzed using Chi-square tests and the generalized linear model. 122 of 1,260 samples (9.68%) were positive for B. henselae infection. The infection rate ranged from 0% to 30.43% and differed significantly among age groups (P < 0.01); infection rate in the 50–59 years group was significantly higher than that in other age groups. The seroprevalence of Bartonella varied significantly among sites within the four provinces, and the infection rate of field workers was significantly higher than that of urban workers.
Resveratrol Induces Apoptosis and Autophagy in T-cell Acute Lymphoblastic Leukemia Cells by Inhibiting Akt/mTOR and Activating p38-MAPK
GE Jiao, LIU Yan, LI Qiang, GUO Xia, GU Ling, MA Zhi Gui, ZHU Yi Ping
2013, 26(11): 902-911.   doi: 10.3967/bes2013.019
[Abstract](1018) [PDF 0KB](32)
An Evaluation of the Investment for Child Development in China
ZHENG Xiao Ying, CHEN Chun Ming, HUANG Cheng Li, Han You Li, QIU Yue, ZHANG Qian Deng, CHEN He
2012, 25(4): 413-420.   doi: 10.3967/0895-3988.2012.04.006
[Abstract](885) [PDF 0KB](31)
Analysis of Protoscoleces-specific Antigens from Echinococcus Granulosus with Proteomics Combined with Western Blot
LI Zong Ji, ZHAO Wei
2012, 25(6): 718-723.   doi: 10.3967/0895-3988.2012.06.015
[Abstract](805) [PDF 0KB](33)
A Study of the Technique of Western Blot for Diagnosis of Lyme Disease caused by Borrelia afzelii in China
LIU Zhi Yun, HAO Qin, HOU Xue Xia, JIANG Yi, GENG Zhen, WU Yi Mou, WAN Kang Lin
2013, 26(3): 190-200.   doi: 10.3967/0895-3988.2013.03.006
[Abstract](881) [PDF 0KB](30)
Interpretation Criteria for Standardized Western Blot for the Predominant Species of Borrelia Burgdorferi Sensu Lato in China
2010, 23(5): 341-349.  
[Abstract](1212) [PDF 0KB](32)
Predictive Values of Body Mass Index and Waist Circumference for Risk Factors of Certain Related Diseases in Chinese Adults - Study on Optimal Cut-off Points of Body Mass Index and Waist Circumference in Chinese Adults
ZHOU Bei-fan
2002, 15(1): 83-96.  
[Abstract](1252) [PDF 0KB](29)
Evaluation of Effectiveness of Integrated Intervention Program in Improving Drug Addicts' Psychological Health1
2008, 21(1): 75-84.  
[Abstract](828) [PDF 0KB](33)
Outline of the Report on Cardiovascular Disease in China, 2010
HU Sheng Shou, KONG Ling Zhi, GAO Run Lin, ZHU Man Lu, WANG Wen, WANG Yong Jun, WU Zhao Su, CHEN Wei Wei, LIU Ming Bo
2012, 25(3): 251-256.   doi: 10.3967/0895-3988.2012.03.001
[Abstract](1507) [PDF 0KB](31)
The Serum Exosome Derived MicroRNA-135a, -193b, and-384 Were Potential Alzheimer's Disease Biomarkers
YANG Ting Ting, LIU Chen Geng, GAO Shi Chao, ZHANG Yi, WANG Pei Chang
2018, 31(2): 87-96.   doi: 10.3967/bes2018.011
[Abstract](965) [FullText HTML](58) [PDF 11332KB](58)
An Investigation of Oxidative DNA Damage in Pharmacy Technicians Exposed to Antineoplastic Drugs in Two Chinese Hospitals Using The Urinary 8-OHdG Assay
HUANG Yu Wen, JIAN Le, ZHANG Mei Bian, ZHOU Quan, YAN Xiao Feng, HUA Xu Dong, ZHOU Ying, HE Ji Liang
2012, 25(1): 109-116.   doi: 10.3967/0895-3988.2012.01.016
[Abstract](825) [PDF 0KB](28)
Report on Childhood Obesity in China (9): Sugar-sweetened Beverages Consumption and Obesity
SHANG Xian Wen, LIU Ai Ling, ZHANG Qian, HU Xiao Qi, DU Song Ming, MA Jun, XU Gui Fa, LI Ying, GUO Hong Wei, DU Lin, LI Ting Yu, MA Guan Sheng
2012, 25(2): 125-132.   doi: 10.3967/0895-3988.2012.02.001
[Abstract](880) [PDF 0KB](29)
Report on Childhood Obesity in China (1) Body Mass Index Reference for Screening Overweight and Obesity in Chinese School-age Children
2005, 18(6): 390-400.  
[Abstract](1548) [PDF 0KB](34)
Oxidative Damage to Lung Tissue and Peripheral Blood in Endotracheal PM2.5-treated Rats
2009, 22(3): 223-228.  
[Abstract](1260) [PDF 0KB](30)
Report on Childhood Obesity in China (10): Association of Sleep Duration with Obesity
MENG Li Ping, LIU Ai Ling, HU Xiao Qi, ZHANG Qian, DU Song Ming, FANG Hong Yun, MA Jun, XU Gui Fa, LI Ying, GUO Hong Wei, DU Lin, MA Guan Sheng
2012, 25(2): 133-140.   doi: 10.3967/0895-3988.2012.02.002
[Abstract](900) [PDF 0KB](32)
Is KPNB3 Locus Associated With Schizophrenia
2007, 20(1): 52-55.  
[Abstract](784) [PDF 0KB](30)
The Association of Overweight and Obesity with Blood Pressure among Chinese Children and Adolescents
DONG Bin, MA Jun, WANG Hai Jun, WANG Zhi Qiang
2013, 26(6): 437-452.   doi: 10.3967/0895-3988.2013.06.004
[Abstract](790) [PDF 0KB](30)
Disease Risks of Childhood Obesity in China
2005, 18(6): 401-410.  
[Abstract](1013) [PDF 0KB](31)
Supplementation of Fermented Barley Extracts with Lactobacillus Plantarum dy-1 Inhibits Obesity via a UCP1-dependent Mechanism
XIAO Xiang, BAI Juan, LI Ming Song, ZHANG Jia Yan, SUN Xin Juan, DONG Ying
2019, 32(8): 578-591.   doi: 10.3967/bes2019.076
[Abstract](1257) [FullText HTML](71) [PDF 9100KB](71)
2008, 21(5).  
[Abstract](596) [PDF 0KB](23)
Trends in Lipids Level and Dyslipidemia among Chinese Adults, 2002-2015
SONG Peng Kun, MAN Qing Qing, LI Hong, PANG Shao Jie, JIA Shan Shan, LI Yu Qian, HE Li, ZHAO Wen Hua, ZHANG Jian
2019, 32(8): 559-570.   doi: 10.3967/bes2019.074
[Abstract](971) [FullText HTML](70) [PDF 3640KB](70)

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Vol 33, No 1

(February, 2020)

ISSN 0895-3988

CN 11-2816 / Q

  • 2018 Impact Factor 2.518

  • 2018 Journal Citation Reports