Volume 22 Issue 6
Dec.  2009
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KANG-CHU LI, SHI-RONG MA, GUI-RONG DING, YAO GUO, GUO-ZHEN GUO. Effects of Electromagnetic Pulse on Bone Metabolism of Mice in vivo[J]. Biomedical and Environmental Sciences, 2009, 22(6): 518-521.
Citation: KANG-CHU LI, SHI-RONG MA, GUI-RONG DING, YAO GUO, GUO-ZHEN GUO. Effects of Electromagnetic Pulse on Bone Metabolism of Mice in vivo[J]. Biomedical and Environmental Sciences, 2009, 22(6): 518-521.

Effects of Electromagnetic Pulse on Bone Metabolism of Mice in vivo

Funds:  the Research Fund of National Natural Science Foundation of China(30800928%30670492)%the National 863 Project(2006 AA02Z4C3)
  • Objective To study the effects of electromagnetic pulse (EMP) on bone metabolism of mice in vivo. Methods Twenty-four male BALB/c mice were divided into a control group and 2 experimental groups (n=8). The whole-body of mice in experimental groups were exposed to 50 kV/m and 400kV/m EMP, 400 pulses daily for 7 consecutive days at 2 seconds intervals. Alkaline phosphotase (ALP) activity, serum calcium concentration and osteocalcin level and trabecular bone volume (BV/TV, %) were measured immediately after EMP exposure by biochemical, ELISA and morphological methods. Results The ALP activity, serum calcium concentration and osteocalcin level and BV/TV in experimental groups remained unchanged after EMP exposure. Conclusion Under our experimental conditions, EMP exposure cannot affect bone metabolism of mice in vivo.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Effects of Electromagnetic Pulse on Bone Metabolism of Mice in vivo

Funds:  the Research Fund of National Natural Science Foundation of China(30800928%30670492)%the National 863 Project(2006 AA02Z4C3)

Abstract: Objective To study the effects of electromagnetic pulse (EMP) on bone metabolism of mice in vivo. Methods Twenty-four male BALB/c mice were divided into a control group and 2 experimental groups (n=8). The whole-body of mice in experimental groups were exposed to 50 kV/m and 400kV/m EMP, 400 pulses daily for 7 consecutive days at 2 seconds intervals. Alkaline phosphotase (ALP) activity, serum calcium concentration and osteocalcin level and trabecular bone volume (BV/TV, %) were measured immediately after EMP exposure by biochemical, ELISA and morphological methods. Results The ALP activity, serum calcium concentration and osteocalcin level and BV/TV in experimental groups remained unchanged after EMP exposure. Conclusion Under our experimental conditions, EMP exposure cannot affect bone metabolism of mice in vivo.

KANG-CHU LI, SHI-RONG MA, GUI-RONG DING, YAO GUO, GUO-ZHEN GUO. Effects of Electromagnetic Pulse on Bone Metabolism of Mice in vivo[J]. Biomedical and Environmental Sciences, 2009, 22(6): 518-521.
Citation: KANG-CHU LI, SHI-RONG MA, GUI-RONG DING, YAO GUO, GUO-ZHEN GUO. Effects of Electromagnetic Pulse on Bone Metabolism of Mice in vivo[J]. Biomedical and Environmental Sciences, 2009, 22(6): 518-521.

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