Volume 36 Issue 8
Sep.  2023
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Method for Folate Deficiency Screening[J]. Biomedical and Environmental Sciences, 2023, 36(8): 784-784. doi: 10.3967/bes2023.108
Citation: Method for Folate Deficiency Screening[J]. Biomedical and Environmental Sciences, 2023, 36(8): 784-784. doi: 10.3967/bes2023.108

Method for Folate Deficiency Screening

doi: 10.3967/bes2023.108
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Method for Folate Deficiency Screening

doi: 10.3967/bes2023.108
Method for Folate Deficiency Screening[J]. Biomedical and Environmental Sciences, 2023, 36(8): 784-784. doi: 10.3967/bes2023.108
Citation: Method for Folate Deficiency Screening[J]. Biomedical and Environmental Sciences, 2023, 36(8): 784-784. doi: 10.3967/bes2023.108
  • This standard specifies the indicators, values, and measurement methods for folate deficiency and insufficiency screening in the people.

    This standard is applicable to the determination of the folate nutritional status in the people.

  • The following documents are essential for the application of this document. For the references dated, only their dated versions are applies to this document; for the references undated, their latest versions, including all amendments, are applicable to this document.

    WS/T 225 Collection and processing of blood samples for clinical chemical testing

  • The following terms and definitions apply to this document.

  • Folate deficiency can be determined when the folate content in serum (or plasma) or red blood cells is lower than the reference values for the normal people.

  • Folate insufficiency can be determined when the average values of folate content in red blood cells for women of reproductive age is lower than the reference values set for preventing neural tube defects.

  • Indicator Value of folate insufficiency
    ng/mL nmol/L
    Folate content in red blood cells < 400 < 906
      Note: This indicator does not apply to the determination of the risk of neural tube defects in individuals.

    Table 1.  Determination of folate insufficiency for women of reproductive age

  • Indicators Values of folate deficiency
    ng/mL nmol/L
    Folate content in serum (or plasma) < 4 < 10
    Folate content in red blood cells < 151 < 340

    Table 2.  Determination of folate deficiency in other people

  • Follow the methods specified in Appendix A.

  • Follow the methods specified in Appendix B.

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