Volume 21 Issue 5
Oct.  2008
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JI-LEI WU, GONG CHEN, XIN-MING SONG, CHENG-FU LI, LEI ZHANG, LAN LIU, XIAO-YING ZHENG. Spatiotemporal Property Analysis of Birth Defects in Wuxi, China[J]. Biomedical and Environmental Sciences, 2008, 21(5): 432-437.
Citation: JI-LEI WU, GONG CHEN, XIN-MING SONG, CHENG-FU LI, LEI ZHANG, LAN LIU, XIAO-YING ZHENG. Spatiotemporal Property Analysis of Birth Defects in Wuxi, China[J]. Biomedical and Environmental Sciences, 2008, 21(5): 432-437.

Spatiotemporal Property Analysis of Birth Defects in Wuxi, China

Funds:  国家重点基础研究发展规划(973计划)(2007CB5119001)%the National Yang Zi Scholar Program%面向21世纪教育振兴行动计划(985计划)(20020903)
  • Objective To describe the temporal trends and spatial patterns of birth defects occurring in Wuxi, a developed region of China. Methods Wavelet analysis was used to decompose the temporal trends of birth defect prevalence based on the birth defect rates over the past 16 years. Birth defect cases with detailed personal and family information were geo-coded and the relative risk in each village was calculated. General G statistic was used to test the spatial property with different scales. Results Wavelet analysis showed an increasing temporal trend of birth defects in this region. Clustering analysis revealed that changes continued in the spatial patterns with different scales. Conclusion Wuxi is confronted with severe challenges to reduce birth defect prevalence. The risk factors are stable and show no change with spatial scale but an increasing temporal trend. Interventions should be focused on villages with a higher prevalence of birth defects.
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通讯作者: 陈斌, bchen63@163.com
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Spatiotemporal Property Analysis of Birth Defects in Wuxi, China

Funds:  国家重点基础研究发展规划(973计划)(2007CB5119001)%the National Yang Zi Scholar Program%面向21世纪教育振兴行动计划(985计划)(20020903)

Abstract: Objective To describe the temporal trends and spatial patterns of birth defects occurring in Wuxi, a developed region of China. Methods Wavelet analysis was used to decompose the temporal trends of birth defect prevalence based on the birth defect rates over the past 16 years. Birth defect cases with detailed personal and family information were geo-coded and the relative risk in each village was calculated. General G statistic was used to test the spatial property with different scales. Results Wavelet analysis showed an increasing temporal trend of birth defects in this region. Clustering analysis revealed that changes continued in the spatial patterns with different scales. Conclusion Wuxi is confronted with severe challenges to reduce birth defect prevalence. The risk factors are stable and show no change with spatial scale but an increasing temporal trend. Interventions should be focused on villages with a higher prevalence of birth defects.

JI-LEI WU, GONG CHEN, XIN-MING SONG, CHENG-FU LI, LEI ZHANG, LAN LIU, XIAO-YING ZHENG. Spatiotemporal Property Analysis of Birth Defects in Wuxi, China[J]. Biomedical and Environmental Sciences, 2008, 21(5): 432-437.
Citation: JI-LEI WU, GONG CHEN, XIN-MING SONG, CHENG-FU LI, LEI ZHANG, LAN LIU, XIAO-YING ZHENG. Spatiotemporal Property Analysis of Birth Defects in Wuxi, China[J]. Biomedical and Environmental Sciences, 2008, 21(5): 432-437.

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