Unusual Patterns of Neural Tube Defects in a High Risk Region of Northern China
Abstract: Objectives To study the prevalence of different types of neural tube defects (NTDs) in Luliang Prefecture, Shanxi province, where the prevalence of NTDs is unusually high and the correlation between NTDs prevalence and patterns. Methods A surveillance population-based birth defects was performed in Luliang Prefecture, Shanxi province. Results The results of our study showed that the prevalence of NTDs was 2-fold higher in Luliang Prefecture than in other areas of Shanxi province. Unusual patterns of NTDs were found, however, multiple NTDs were relatively common in Luliang Prefecture, accounting for over 13% of all NTDs cases in China. Conclusion The prevalence of NTDs is associated with its patterns.
|Citation:||GONG CHEN, LI-JUN PEI, JIAN HUANG, XIN-MING SONG, LIANG-MING LIN, XUE GU, JIAN-XINWU, FANG WANG, JI-LEI WU, JIA-PENG CHEN, JU-FEN LIU, RUO-LEI XIN, TING ZHANG, XIAO-YING ZHENG. Unusual Patterns of Neural Tube Defects in a High Risk Region of Northern China[J]. Biomedical and Environmental Sciences, 2009, 22(4): 340-344.|