Tuberculosis Control Priorities Defined by Using Cost-Effectiveness and Burden of Disease
- Tuberculosis (TB) /
- Burden of disease (BOD) /
- Disability adjusted life year (DALY) /
- Cost-effectiveness ratio (CER)
Abstract: Objective To define TB control priorities using cost-effectiveness and burden of disease. Methods An assumed cohort of 2 000 cases was set up based on age-specific incidence of 794 newly registered smear-positive cases in Beijing in 1994. Prognostic trees and model diagrams of infectivity with natural history and DOTS intervention were constructed based on the epidemiological parameters. Results DOTS reduced 89.19 % of YLL, 78.90% of YLD, and 99.98% of infectivity BOD. One DALY could be saved with 45.70 Yuan by DOTS with 3% discount. Sensitivity analysis showed that discount had effect on CER. Weight of age was insensitive to CER. The higher the DOTS cured rate, the more the cost-effectiveness. Conclusions DOTS is a good cost-effectiveness TB control strategy. Cost-effectiveness and burden of disease can be used to define TB control priorities.
|Citation:||XU Qun, WU Zheng-lai, JIN SHUI-GAO, ZHANG LiX-ing. Tuberculosis Control Priorities Defined by Using Cost-Effectiveness and Burden of Disease[J]. Biomedical and Environmental Sciences, 2002, 15(2): 172-176.|