XU Tian; ZHANG Jin Tao; YANG Mei; ZHANG Huan; LIU Wen Qing; KONG Yan; XU Tan; ZHANG Yong Hong

doi:10.3967/bes2014.023

doi: 10.3967/bes2014.023

基金项目: This study was supported by the National Natural Science Foundation ofChina(Grant 81172761)%a Project of the PriorityAcademic Program Development of Jiangsu Higher Education Institutions

Dyslipidemia and Outcome in Patients with Acute Ischemic Stroke

Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou215123, Jiangsu, China
Department of Neurology, Chinese PLA 88 Hospital, Tai’an 271000, Shandong,China
Department of 0phthalmology,Affiliated Hospital of Nantong University,Nantong 226001, Jiangsu, China

Funds: This study was supported by the National Natural Science Foundation ofChina(Grant 81172761)%a Project of the PriorityAcademic Program Development of Jiangsu Higher Education Institutions

摘要: ObjectiveTo study the relationship between dyslipidemia and outcome in patients with acute ischemic stroke.
MethodsData about 1 568 patients with acute ischemic stroke werecollected from 4 hospitals in Shandong Province from January 2006 to December 2008. National Institute of Health Stroke Scale (NIHSS) >10 at discharge or death was defined as the outcome. Effect of dyslipidemia on outcome in patients with acute ischemic stroke was analyzed by multivariate logistic regression analysis and propensity score-adjusted analysis, respectively.
ResultsThe serum levels of TC, LDL-C, and HDL-C were significantly associated with the outcome in patients with acute ischemic stroke. Multivariate logistic regression analysis and propensity score-adjusted analysis showed that the ORs and 95% CIs were 3.013 (1.259, 7.214)/2.655 (1.298, 5.43), 3.157(1.306, 7.631)/3.405(1.621, 7.154), and 0.482 (0.245, 0.946)/0.51 (0.282, 0.921), respectively, for patients with acute ischemic stroke. Hosmer-Lemeshow goodness-of-fit test showed no significant difference in observed and predicted risk in patients with acute ischemic stroke (chi-square=8.235, P=0.411).
ConclusionSerum levels of TC, LDL-C, and HDL-C are positively related with the outcome in patients with acute ischemic stroke.
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Abstract: ObjectiveTo study the relationship between dyslipidemia and outcome in patients with acute ischemic stroke.
MethodsData about 1 568 patients with acute ischemic stroke werecollected from 4 hospitals in Shandong Province from January 2006 to December 2008. National Institute of Health Stroke Scale (NIHSS) >10 at discharge or death was defined as the outcome. Effect of dyslipidemia on outcome in patients with acute ischemic stroke was analyzed by multivariate logistic regression analysis and propensity score-adjusted analysis, respectively.
ResultsThe serum levels of TC, LDL-C, and HDL-C were significantly associated with the outcome in patients with acute ischemic stroke. Multivariate logistic regression analysis and propensity score-adjusted analysis showed that the ORs and 95% CIs were 3.013 (1.259, 7.214)/2.655 (1.298, 5.43), 3.157(1.306, 7.631)/3.405(1.621, 7.154), and 0.482 (0.245, 0.946)/0.51 (0.282, 0.921), respectively, for patients with acute ischemic stroke. Hosmer-Lemeshow goodness-of-fit test showed no significant difference in observed and predicted risk in patients with acute ischemic stroke (chi-square=8.235, P=0.411).
ConclusionSerum levels of TC, LDL-C, and HDL-C are positively related with the outcome in patients with acute ischemic stroke.
- Dyslipidemia /
- Acute ischemic stroke /
- Outcome /
- Multivariate logistic regression analysis /
- Propensity score-adjusted analysis

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doi: 10.3967/bes2014.023

Dyslipidemia and Outcome in Patients with Acute Ischemic Stroke

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Dyslipidemia and Outcome in Patients with Acute Ischemic Stroke

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Dyslipidemia and Outcome in Patients with Acute Ischemic Stroke

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doi: 10.3967/bes2014.023

Dyslipidemia and Outcome in Patients with Acute Ischemic Stroke

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Dyslipidemia and Outcome in Patients with Acute Ischemic Stroke

doi: 10.3967/bes2014.023

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Dyslipidemia and Outcome in Patients with Acute Ischemic Stroke

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