Volume 27 Issue 8
Nov.  2019
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DENG Xin Ru, ZHANG Yin Fei, WANG Tian Ge, XU Bai Hui, SUN Ji Chao, ZHAO Lie Bin, XU Min, CHEN Yu Hong, WANG Wei Qing, BI Yu Fang, LU Jie Li. Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese[J]. Biomedical and Environmental Sciences, 2014, 27(8): 594-600. doi: 10.3967/bes2014.091
Citation: DENG Xin Ru, ZHANG Yin Fei, WANG Tian Ge, XU Bai Hui, SUN Ji Chao, ZHAO Lie Bin, XU Min, CHEN Yu Hong, WANG Wei Qing, BI Yu Fang, LU Jie Li. Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese[J]. Biomedical and Environmental Sciences, 2014, 27(8): 594-600. doi: 10.3967/bes2014.091

Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese

doi: 10.3967/bes2014.091
Funds:  the Key Laboratory for Endocrine and Metabolic Diseases, Ministry of Health(1994DP131044)%National Nature Science Foundation of China(81170739,81170719,81222008,81370960)%Shanghai New Excel ent Youth Program(XYQ2011009)%Shanghai Health Bureau(2011293)%EFSD-CDS-Lilly Program for Collaborative Research between China and Europe(2011)%Shanghai Shen Kang Hospital Development Center(SHDC12012301)
  • Objective To study the relation between serum calcium level and elevated BaPWV in Chinese subjects.
    Methods The relation between serum calcium level and elevated BaPWV was studied in 9 615 subjects. The mean value of left and right BaPWV was analyzed. BaPWV was defined as high when it was31 752.5 cm/s (the upper quartile) either side.
    Results The BaPWV and its elevated percentage progressively increased across the quartiles of the serum calcium level (P<0.05). The prevalence of elevated BaPWV was significantly higher in subjects of the second, third and highest quartiles than in those of the lowest quartile (26.9%, 28.4%, and 33.2%vs 23.7%, P=0.0116, P=0.0004, and P<0.0001). Logistic regression analysis revealed that the risk of elevated BaPWV was 1.32- fold higher in subjects of the highest quartile than in those of the lowest quartile (OR=1.32, 95%CI:1.08-1.60).
    Conclusion The elevated serum calcium level is related to an elevated BaPWV and a higher risk of arterial stiffness, independent of conventional risk factors, in middle-aged and elderly Chinese subjects.
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通讯作者: 陈斌, bchen63@163.com
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese

doi: 10.3967/bes2014.091
Funds:  the Key Laboratory for Endocrine and Metabolic Diseases, Ministry of Health(1994DP131044)%National Nature Science Foundation of China(81170739,81170719,81222008,81370960)%Shanghai New Excel ent Youth Program(XYQ2011009)%Shanghai Health Bureau(2011293)%EFSD-CDS-Lilly Program for Collaborative Research between China and Europe(2011)%Shanghai Shen Kang Hospital Development Center(SHDC12012301)

Abstract: Objective To study the relation between serum calcium level and elevated BaPWV in Chinese subjects.
Methods The relation between serum calcium level and elevated BaPWV was studied in 9 615 subjects. The mean value of left and right BaPWV was analyzed. BaPWV was defined as high when it was31 752.5 cm/s (the upper quartile) either side.
Results The BaPWV and its elevated percentage progressively increased across the quartiles of the serum calcium level (P<0.05). The prevalence of elevated BaPWV was significantly higher in subjects of the second, third and highest quartiles than in those of the lowest quartile (26.9%, 28.4%, and 33.2%vs 23.7%, P=0.0116, P=0.0004, and P<0.0001). Logistic regression analysis revealed that the risk of elevated BaPWV was 1.32- fold higher in subjects of the highest quartile than in those of the lowest quartile (OR=1.32, 95%CI:1.08-1.60).
Conclusion The elevated serum calcium level is related to an elevated BaPWV and a higher risk of arterial stiffness, independent of conventional risk factors, in middle-aged and elderly Chinese subjects.

DENG Xin Ru, ZHANG Yin Fei, WANG Tian Ge, XU Bai Hui, SUN Ji Chao, ZHAO Lie Bin, XU Min, CHEN Yu Hong, WANG Wei Qing, BI Yu Fang, LU Jie Li. Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese[J]. Biomedical and Environmental Sciences, 2014, 27(8): 594-600. doi: 10.3967/bes2014.091
Citation: DENG Xin Ru, ZHANG Yin Fei, WANG Tian Ge, XU Bai Hui, SUN Ji Chao, ZHAO Lie Bin, XU Min, CHEN Yu Hong, WANG Wei Qing, BI Yu Fang, LU Jie Li. Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese[J]. Biomedical and Environmental Sciences, 2014, 27(8): 594-600. doi: 10.3967/bes2014.091

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