Elevated Resting Heart Rate is Associated with Dyslipidemia in Middle-aged and Elderly Chinese

SUN Ji Chao; HUANG Xiao Lin; DENG Xin Ru; LV Xiao Fei; LU Jie Li; CHEN Yu Hong; BI Yu Fang; WANG Wei Qing; XU Min; NING Guang

doi:10.3967/bes2014.092

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Volume 27 Issue 8

Aug. 2014

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Article Navigation > Biomedical and Environmental Sciences > 2014 > 27(8): 601-605

SUN Ji Chao, HUANG Xiao Lin, DENG Xin Ru, LV Xiao Fei, LU Jie Li, CHEN Yu Hong, BI Yu Fang, WANG Wei Qing, XU Min, NING Guang. Elevated Resting Heart Rate is Associated with Dyslipidemia in Middle-aged and Elderly Chinese[J]. Biomedical and Environmental Sciences, 2014, 27(8): 601-605. doi: 10.3967/bes2014.092

Citation:

SUN Ji Chao, HUANG Xiao Lin, DENG Xin Ru, LV Xiao Fei, LU Jie Li, CHEN Yu Hong, BI Yu Fang, WANG Wei Qing, XU Min, NING Guang. Elevated Resting Heart Rate is Associated with Dyslipidemia in Middle-aged and Elderly Chinese[J]. Biomedical and Environmental Sciences, 2014, 27(8): 601-605. doi: 10.3967/bes2014.092

Elevated Resting Heart Rate is Associated with Dyslipidemia in Middle-aged and Elderly Chinese

doi: 10.3967/bes2014.092

Key Laboratory for Endocrine and Metabolic Diseases, Ministry of Health, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, E-Institute of Shanghai Universities, Shanghai 200025, China

Funds: grants from the Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health(1994DP131044)%National Nature Science Foundation of China(81170739,81170719,81270877,81222008)%Shanghai New Excel ent Youth Program(XYQ2011009)%the Shanghai Health Bureau Grant(2011293)

Abstract

Objective To study the relationship between resting heart rate and blood lipid level.
Methods A total of 9 415 subjects aged≥40 years were included in the present study. Their resting heart rate was monitored and their serum levels of triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were measured to define dyslipidemia according to the 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults.
Results The subjects were divided into group A with their resting heart rate<70 beats/min, group B with their resting heart rate=70-79 beats/min, group C with their resting heart rate=80-89 beats/min, and group D with their resting heart rate≥90 beats/min. High TG, TC, and LDL-C were presented across the resting heart rate (Ptrend<0.01). Multiple logistic regression analysis revealed that the risk of high TG and TC was higher in subjects with their resting heart rate≥90 beats/min than in those with their resting heart rate<70 beats/min (OR=1.42;95%CI:1.16-1.74 and OR=1.33;95%CI:1.09-1.64, respectively).
Conclusion Elevated resting heart rate is associated with high TG and TC in middle-aged and elderly Chinese subjects.
- Dyslipidemia,
- Heart rate,
- Triglyceride,
- Cholesterol
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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Elevated Resting Heart Rate is Associated with Dyslipidemia in Middle-aged and Elderly Chinese

doi: 10.3967/bes2014.092

Key Laboratory for Endocrine and Metabolic Diseases, Ministry of Health, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, E-Institute of Shanghai Universities, Shanghai 200025, China

Key words:

Abstract: Objective To study the relationship between resting heart rate and blood lipid level.
Methods A total of 9 415 subjects aged≥40 years were included in the present study. Their resting heart rate was monitored and their serum levels of triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were measured to define dyslipidemia according to the 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults.
Results The subjects were divided into group A with their resting heart rate<70 beats/min, group B with their resting heart rate=70-79 beats/min, group C with their resting heart rate=80-89 beats/min, and group D with their resting heart rate≥90 beats/min. High TG, TC, and LDL-C were presented across the resting heart rate (Ptrend<0.01). Multiple logistic regression analysis revealed that the risk of high TG and TC was higher in subjects with their resting heart rate≥90 beats/min than in those with their resting heart rate<70 beats/min (OR=1.42;95%CI:1.16-1.74 and OR=1.33;95%CI:1.09-1.64, respectively).
Conclusion Elevated resting heart rate is associated with high TG and TC in middle-aged and elderly Chinese subjects.

Citation:

SUN Ji Chao, HUANG Xiao Lin, DENG Xin Ru, LV Xiao Fei, LU Jie Li, CHEN Yu Hong, BI Yu Fang, WANG Wei Qing, XU Min, NING Guang. Elevated Resting Heart Rate is Associated with Dyslipidemia in Middle-aged and Elderly Chinese[J]. Biomedical and Environmental Sciences, 2014, 27(8): 601-605. doi: 10.3967/bes2014.092