Volume 28 Issue 9
Nov.  2019
Turn off MathJax
Article Contents

GAO Lei, XI Qian Qian, WU Jun, HAN Yu, DAI Wei, SU Yuan Yuan, ZHANG Xin. Association between Prenatal Environmental Factors and Child Autism:A Case Control Study in Tianjin, China[J]. Biomedical and Environmental Sciences, 2015, 28(9): 642-650. doi: 10.3967/bes2015.090
Citation: GAO Lei, XI Qian Qian, WU Jun, HAN Yu, DAI Wei, SU Yuan Yuan, ZHANG Xin. Association between Prenatal Environmental Factors and Child Autism:A Case Control Study in Tianjin, China[J]. Biomedical and Environmental Sciences, 2015, 28(9): 642-650. doi: 10.3967/bes2015.090

Association between Prenatal Environmental Factors and Child Autism:A Case Control Study in Tianjin, China

doi: 10.3967/bes2015.090
Funds:  The study was support by the National Natural Science Foundation of China Grant No.81072313
  • Objective To investigate the association between autism and prenatal environmental risk factors.
    Methods A case-control study was conducted among 193 children with autism from the special educational schools and 733 typical development controls matched by age and gender by using questionnaire in Tianjin from 2007 to 2012. Statistical analysis included quick unbiased efficient statistical tree (QUEST) and logistic regression in SPSS 20.0.
    Results There were four predictors by QUEST and the logistic regression analysis, maternal air conditioner use during pregnancy (OR=0.316, 95% CI: 0.215-0.463) was the single first-level node (χ2=50.994, P=0.000); newborn complications (OR=4.277, 95% CI: 2.314-7.908) and paternal consumption of freshwater fish (OR=0.383, 95% CI: 0.256-0.573) were second-layer predictors (χ2=45.248, P=0.000; χ2=24.212, P=0.000); and maternal depression (OR=4.822, 95% CI: 3.047-7.631) was the single third-level predictor (χ2=23.835, P=0.000). The prediction accuracy of the tree was 89.2%.
    Conclusion The air conditioner use during pregnancy and paternal freshwater fish diet might be beneficial for the prevention of autism, while newborn complications and maternal depression might be the risk factors.
  • 加载中
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(729) PDF downloads(67) Cited by()

Proportional views
Related

Association between Prenatal Environmental Factors and Child Autism:A Case Control Study in Tianjin, China

doi: 10.3967/bes2015.090
Funds:  The study was support by the National Natural Science Foundation of China Grant No.81072313

Abstract: Objective To investigate the association between autism and prenatal environmental risk factors.
Methods A case-control study was conducted among 193 children with autism from the special educational schools and 733 typical development controls matched by age and gender by using questionnaire in Tianjin from 2007 to 2012. Statistical analysis included quick unbiased efficient statistical tree (QUEST) and logistic regression in SPSS 20.0.
Results There were four predictors by QUEST and the logistic regression analysis, maternal air conditioner use during pregnancy (OR=0.316, 95% CI: 0.215-0.463) was the single first-level node (χ2=50.994, P=0.000); newborn complications (OR=4.277, 95% CI: 2.314-7.908) and paternal consumption of freshwater fish (OR=0.383, 95% CI: 0.256-0.573) were second-layer predictors (χ2=45.248, P=0.000; χ2=24.212, P=0.000); and maternal depression (OR=4.822, 95% CI: 3.047-7.631) was the single third-level predictor (χ2=23.835, P=0.000). The prediction accuracy of the tree was 89.2%.
Conclusion The air conditioner use during pregnancy and paternal freshwater fish diet might be beneficial for the prevention of autism, while newborn complications and maternal depression might be the risk factors.

GAO Lei, XI Qian Qian, WU Jun, HAN Yu, DAI Wei, SU Yuan Yuan, ZHANG Xin. Association between Prenatal Environmental Factors and Child Autism:A Case Control Study in Tianjin, China[J]. Biomedical and Environmental Sciences, 2015, 28(9): 642-650. doi: 10.3967/bes2015.090
Citation: GAO Lei, XI Qian Qian, WU Jun, HAN Yu, DAI Wei, SU Yuan Yuan, ZHANG Xin. Association between Prenatal Environmental Factors and Child Autism:A Case Control Study in Tianjin, China[J]. Biomedical and Environmental Sciences, 2015, 28(9): 642-650. doi: 10.3967/bes2015.090

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return