Volume 29 Issue 5
Nov.  2019
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ZHANG Lei, JIANG Ding Guo, SUI Hai Xia, WU Ping Gu, LIU Ai Dong, YANG Da Jin, LIU Zhao Ping, SONG Yan, LI Ning. Dietary Exposure to Benzyl Butyl Phthalate in China[J]. Biomedical and Environmental Sciences, 2016, 29(5): 365-373. doi: 10.3967/bes2016.047
Citation: ZHANG Lei, JIANG Ding Guo, SUI Hai Xia, WU Ping Gu, LIU Ai Dong, YANG Da Jin, LIU Zhao Ping, SONG Yan, LI Ning. Dietary Exposure to Benzyl Butyl Phthalate in China[J]. Biomedical and Environmental Sciences, 2016, 29(5): 365-373. doi: 10.3967/bes2016.047

Dietary Exposure to Benzyl Butyl Phthalate in China

doi: 10.3967/bes2016.047
Funds:  This work was partialy supported by China's Ministry ofScience & Technology (2014ZX09304307)
  • ObjectiveBenzyl butyl phthalate (BBP) is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population.
    MethodsThe BBP contents were detected in 7409 food samples from 25 foodcategories by gas chromatography-mass spectrometry operated in selected ion monitoring (SIM) mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake (TDI) of BBP established by European Food safety Agency.
    ResultsIt was found that BBP was undetectable in most samples and the highest level was 1.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged≥2 years was
    1.03 μg/kgbw perday and the highest average exposure was found in 2-6 years old children (1.98 μg/kg bw perday). The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake (TDI) in worst scenario.
    ConclusionThe health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Dietary Exposure to Benzyl Butyl Phthalate in China

doi: 10.3967/bes2016.047
Funds:  This work was partialy supported by China's Ministry ofScience & Technology (2014ZX09304307)

Abstract: ObjectiveBenzyl butyl phthalate (BBP) is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population.
MethodsThe BBP contents were detected in 7409 food samples from 25 foodcategories by gas chromatography-mass spectrometry operated in selected ion monitoring (SIM) mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake (TDI) of BBP established by European Food safety Agency.
ResultsIt was found that BBP was undetectable in most samples and the highest level was 1.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged≥2 years was
1.03 μg/kgbw perday and the highest average exposure was found in 2-6 years old children (1.98 μg/kg bw perday). The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake (TDI) in worst scenario.
ConclusionThe health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.

ZHANG Lei, JIANG Ding Guo, SUI Hai Xia, WU Ping Gu, LIU Ai Dong, YANG Da Jin, LIU Zhao Ping, SONG Yan, LI Ning. Dietary Exposure to Benzyl Butyl Phthalate in China[J]. Biomedical and Environmental Sciences, 2016, 29(5): 365-373. doi: 10.3967/bes2016.047
Citation: ZHANG Lei, JIANG Ding Guo, SUI Hai Xia, WU Ping Gu, LIU Ai Dong, YANG Da Jin, LIU Zhao Ping, SONG Yan, LI Ning. Dietary Exposure to Benzyl Butyl Phthalate in China[J]. Biomedical and Environmental Sciences, 2016, 29(5): 365-373. doi: 10.3967/bes2016.047

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