Method for Vitamin D Deficiency Screening

This standard specifies the indicators, reference values, and measurement methods for vitamin D deficiency and insufficiency screening in the people.

This standard is applicable to the determination of vitamin D nutritional status in the people.

The following documents are essential for the application of this document. For the references dated, only their dated versions are applies to this document; for the references undated, their latest versions, including all amendments, are applicable to this document.

GB/T 603 Chemical reagent Preparation of formulations and products used in test methods

GB/T 6682 Analysis of laboratory water specifications and test methods

WS/T 225 Collection and processing of blood samples for clinical chemical testing

The following terms and definitions apply to this document.

The main circulating form of vitamin D in the blood, with good stability, is recognized as a reliable indicator for evaluating the nutritional status of vitamin D in the human body. It mainly includes two forms: 25 (OH) D₂ and 25 (OH) D₃, of which 25 (OH) D₃ is the main form of vitamin D present in the blood.

Vitamin D deficiency can be determined when the content of 25-hydroxyvitamin D in human serum (or plasma) is lower than the reference values for deficiency.

Vitamin D insufficiency can be determined when the content of 25-hydroxyvitamin D in human serum (or plasma) is lower than the reference values for the normal people, but higher than that for deficiency.

Determination indicators and reference values for vitamin D nutritional status in the people are shown in Table 1.

Follow the methods specified in Appendix A.

Follow the methods specified in Appendix B.

Follow the methods specified in Appendix C.

Follow the methods specified in Appendix D.