Volume 17 Issue 4
Nov.  2019
Turn off MathJax
Article Contents

Xiao-ying ZHENG, Ting ZHANG, Yi-Fei WANG, CHEN XU, GONG Chen, RUOLEI XIN, JIA-PENG CHEN, XU-MEI HU, QING YANG, XIN-MING SONG, LI-HUA PANG, YING JI, HONG-MEI SUN, LEI ZHANG, JU-FEN LIU, YAN-LING GUO, YAN ZHANG. Intrauterine Infections and Birth Defects[J]. Biomedical and Environmental Sciences, 2004, 17(4): 476-491.
Citation: Xiao-ying ZHENG, Ting ZHANG, Yi-Fei WANG, CHEN XU, GONG Chen, RUOLEI XIN, JIA-PENG CHEN, XU-MEI HU, QING YANG, XIN-MING SONG, LI-HUA PANG, YING JI, HONG-MEI SUN, LEI ZHANG, JU-FEN LIU, YAN-LING GUO, YAN ZHANG. Intrauterine Infections and Birth Defects[J]. Biomedical and Environmental Sciences, 2004, 17(4): 476-491.

Intrauterine Infections and Birth Defects

Funds:  This work was supported(2001CB5103)%国家重点基础研究发展计划(973计划)(30025042,30070790)%国家自然科学基金(02158)%面向21世纪教育振兴行动计划(985计划)
  • Intrauterine infection is an important cause of some birth defects worldwide. The most common pathogens include rubella virus, cytomegaloviurs, ureaplasma urealyticum, toxoplasma, etc. General information about these pathogens in epidemiology, consequence of birth defects, and the possible mechanisms in the progress of birth defects, and the interventions to prevent or treat these pathogens' infections are described. The infections caused by rubella virus, cytomegaloviurs, ureaplasma urealyticum, toxoplasma, etc. are common, yet they are proved to be fatal during the pregnant period, especially during the first trimester. These infections may cause sterility, abortion, stillbirth, low birth weight, and affect multiple organs that may induce loss of hearing and vision, even fetal deformity and the long-term effects. These pathogens' infections may influence the microenvironment of placenta, including levels of enzymes and cytokines, and affect chondriosome that may induce the progress of birth defect. Early diagnosis of infections during pregnancy should be strengthened. There are still many things to be settled, such as the molecular mechanisms of birth defects, the effective vaccines to certain pathogens. Birth defect researches in terms of etiology and the development of applicable and sensitive pathogen detection technology and methods are imperative.
  • 加载中
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(764) PDF downloads(14) Cited by()

Proportional views
Related

Intrauterine Infections and Birth Defects

Funds:  This work was supported(2001CB5103)%国家重点基础研究发展计划(973计划)(30025042,30070790)%国家自然科学基金(02158)%面向21世纪教育振兴行动计划(985计划)

Abstract: Intrauterine infection is an important cause of some birth defects worldwide. The most common pathogens include rubella virus, cytomegaloviurs, ureaplasma urealyticum, toxoplasma, etc. General information about these pathogens in epidemiology, consequence of birth defects, and the possible mechanisms in the progress of birth defects, and the interventions to prevent or treat these pathogens' infections are described. The infections caused by rubella virus, cytomegaloviurs, ureaplasma urealyticum, toxoplasma, etc. are common, yet they are proved to be fatal during the pregnant period, especially during the first trimester. These infections may cause sterility, abortion, stillbirth, low birth weight, and affect multiple organs that may induce loss of hearing and vision, even fetal deformity and the long-term effects. These pathogens' infections may influence the microenvironment of placenta, including levels of enzymes and cytokines, and affect chondriosome that may induce the progress of birth defect. Early diagnosis of infections during pregnancy should be strengthened. There are still many things to be settled, such as the molecular mechanisms of birth defects, the effective vaccines to certain pathogens. Birth defect researches in terms of etiology and the development of applicable and sensitive pathogen detection technology and methods are imperative.

Xiao-ying ZHENG, Ting ZHANG, Yi-Fei WANG, CHEN XU, GONG Chen, RUOLEI XIN, JIA-PENG CHEN, XU-MEI HU, QING YANG, XIN-MING SONG, LI-HUA PANG, YING JI, HONG-MEI SUN, LEI ZHANG, JU-FEN LIU, YAN-LING GUO, YAN ZHANG. Intrauterine Infections and Birth Defects[J]. Biomedical and Environmental Sciences, 2004, 17(4): 476-491.
Citation: Xiao-ying ZHENG, Ting ZHANG, Yi-Fei WANG, CHEN XU, GONG Chen, RUOLEI XIN, JIA-PENG CHEN, XU-MEI HU, QING YANG, XIN-MING SONG, LI-HUA PANG, YING JI, HONG-MEI SUN, LEI ZHANG, JU-FEN LIU, YAN-LING GUO, YAN ZHANG. Intrauterine Infections and Birth Defects[J]. Biomedical and Environmental Sciences, 2004, 17(4): 476-491.

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return