Volume 24 Issue 3
Jun.  2011
Turn off MathJax
Article Contents

HUANG HuaPin, CHE ChunHui, LIU ChangYun, HANG Fang, MAO XiaoHong. Factors Associated with Generic and Disease-specific Quality of Life in Epilepsy[J]. Biomedical and Environmental Sciences, 2011, 24(3): 228-233. doi: 10.3967/0895-3988.2011.03.004
Citation: HUANG HuaPin, CHE ChunHui, LIU ChangYun, HANG Fang, MAO XiaoHong. Factors Associated with Generic and Disease-specific Quality of Life in Epilepsy[J]. Biomedical and Environmental Sciences, 2011, 24(3): 228-233. doi: 10.3967/0895-3988.2011.03.004

Factors Associated with Generic and Disease-specific Quality of Life in Epilepsy

doi: 10.3967/0895-3988.2011.03.004
  • Objective To investigate the association between quality of life (QOL) and sociodemographic factors, clinical seizure factors, depression and anxiety in patients suffering from epilepsy.Methods We examined 141 consecutive patients with epilepsy (mean age 25.8±9.6, 61.7% male). All patients completed the Self-Rating Depression Scale, Self-Rating Anxiety Scale , WHOQOL-BREF and QOLIE-31(Chinese version). Multiple linear regression analyses were applied to investigate factors impact on QOL.Results The results revealed that scores on two domains of the WHOQOL-BREF (i.e., physical and psychological domains, P<0.05) were significantly lower in the epilepsy group compared with the control group. Multiple regression analyses showed that anxiety, depression and course explained approximately 40% of the variance in patients' QOL. Anxiety was consistently the strongest predictor of lower scores on almost all QOL domains. In addition, the severity of depressive symptoms was significantly associated with lower scores across many QOL domains.Conclusion Our findings suggest that QOLIE scores might be substantially affected by the presence and severity of anxiety symptoms and, to a lesser degree, of depressive symptoms and prolonged course of illness. In contrast, clinical seizure variables had a weaker association with QOL. Healthcare professionals should be aware of the significance of patients' emotional state and of the role it plays in their QOL.
  • 加载中
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(1566) PDF downloads(21) Cited by()

Proportional views
Related

Factors Associated with Generic and Disease-specific Quality of Life in Epilepsy

doi: 10.3967/0895-3988.2011.03.004

Abstract: Objective To investigate the association between quality of life (QOL) and sociodemographic factors, clinical seizure factors, depression and anxiety in patients suffering from epilepsy.Methods We examined 141 consecutive patients with epilepsy (mean age 25.8±9.6, 61.7% male). All patients completed the Self-Rating Depression Scale, Self-Rating Anxiety Scale , WHOQOL-BREF and QOLIE-31(Chinese version). Multiple linear regression analyses were applied to investigate factors impact on QOL.Results The results revealed that scores on two domains of the WHOQOL-BREF (i.e., physical and psychological domains, P<0.05) were significantly lower in the epilepsy group compared with the control group. Multiple regression analyses showed that anxiety, depression and course explained approximately 40% of the variance in patients' QOL. Anxiety was consistently the strongest predictor of lower scores on almost all QOL domains. In addition, the severity of depressive symptoms was significantly associated with lower scores across many QOL domains.Conclusion Our findings suggest that QOLIE scores might be substantially affected by the presence and severity of anxiety symptoms and, to a lesser degree, of depressive symptoms and prolonged course of illness. In contrast, clinical seizure variables had a weaker association with QOL. Healthcare professionals should be aware of the significance of patients' emotional state and of the role it plays in their QOL.

HUANG HuaPin, CHE ChunHui, LIU ChangYun, HANG Fang, MAO XiaoHong. Factors Associated with Generic and Disease-specific Quality of Life in Epilepsy[J]. Biomedical and Environmental Sciences, 2011, 24(3): 228-233. doi: 10.3967/0895-3988.2011.03.004
Citation: HUANG HuaPin, CHE ChunHui, LIU ChangYun, HANG Fang, MAO XiaoHong. Factors Associated with Generic and Disease-specific Quality of Life in Epilepsy[J]. Biomedical and Environmental Sciences, 2011, 24(3): 228-233. doi: 10.3967/0895-3988.2011.03.004

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return