Histological Subtypes of Lung Cancer in Chinese Males from 2000 to 2012

ZOU Xiao Nong; LIN Dong Mei; WAN Xia; CHAO Ann; FENG Qin Fu; DAI Zhen; YANG Gong Huan; LV Ning

doi:10.3967/bes2014.010

PDF
Cite
Share

facebook

twitter

google

linkedin

Volume 27 Issue 1

Jan. 2014

Turn off MathJax

Article Contents

Article Navigation > Biomedical and Environmental Sciences > 2014 > 27(1): 3-9

ZOU Xiao Nong, LIN Dong Mei, WAN Xia, CHAO Ann, FENG Qin Fu, DAI Zhen, YANG Gong Huan, LV Ning. Histological Subtypes of Lung Cancer in Chinese Males from 2000 to 2012[J]. Biomedical and Environmental Sciences, 2014, 27(1): 3-9. doi: 10.3967/bes2014.010

Citation:

ZOU Xiao Nong, LIN Dong Mei, WAN Xia, CHAO Ann, FENG Qin Fu, DAI Zhen, YANG Gong Huan, LV Ning. Histological Subtypes of Lung Cancer in Chinese Males from 2000 to 2012[J]. Biomedical and Environmental Sciences, 2014, 27(1): 3-9. doi: 10.3967/bes2014.010

Histological Subtypes of Lung Cancer in Chinese Males from 2000 to 2012

doi: 10.3967/bes2014.010

National 0ffice of Cancer Prevention and Control, Cancer Institute/Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China
Department of Pathology, Chinese Academy of Medical Sciences, Beijing 100021, China
Center for Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China
Center for Global Health, National Cancer Institute, Bethesda MD, USA
Department of Radiation 0ncology, Chinese Academy of Medical Sciences, Beijing 100021, China

Funds: NIH Project‘Epidemiology and Intervention Research for Tobacco Control in China’(R01 RFA-TW-06-006)%Beijing Run-for-Hope Fund(YF2010-48)

Abstract

Objective To characterize the histological and epidemiological features of male lung cancer patients in China.
Methods The demographic and histological information about male lung cancer patients identified from 2000-01-01 to 2012-12-31, was collected from the Cancer Hospital of the Chinese Academy of Medical Sciences. Relative frequencies (RF) were estimated for major histological subtypes and compared according to the years of diagnosis and birth.
Results The RF of adenocarcinoma (ADC) increased from 21.96% to 43.36% and the RF of squamous cell carcinoma (SCC) decreased from 39.11% to 32.23% from 2000 to 2012 in the 15 427 male lung cancer patients included in this study (Z=17.909, P<0.0001; Z=-6.117, P<0.0001). The RF of ADC increased from 28.72% in 2000-2004, 36.88% in 2005-2008 to 48.61% in 2009-2012 in patients born after 1960. The age-adjusted RF of ADC in 2007-2012 increased consistently in all the investigated areas.
Conclusion The increased RF of ADC in male lung cancer patients highlights the need for further investigation of the etiologic factors of these tumors. Smoke-free policies rather than modifying tobacco products should be enforced.
- Epidemiology,
- Lung cancer,
- Histology
References
Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views(1669) PDF downloads(112) Cited by()

Proportional views

Histological Subtypes of Lung Cancer in Chinese Males from 2000 to 2012

doi: 10.3967/bes2014.010

National 0ffice of Cancer Prevention and Control, Cancer Institute/Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China

Department of Pathology, Chinese Academy of Medical Sciences, Beijing 100021, China

Center for Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China

Center for Global Health, National Cancer Institute, Bethesda MD, USA

Department of Radiation 0ncology, Chinese Academy of Medical Sciences, Beijing 100021, China

Funds: NIH Project‘Epidemiology and Intervention Research for Tobacco Control in China’(R01 RFA-TW-06-006)%Beijing Run-for-Hope Fund(YF2010-48)

Key words:

Epidemiology /
Lung cancer /
Histology

Abstract: Objective To characterize the histological and epidemiological features of male lung cancer patients in China.
Methods The demographic and histological information about male lung cancer patients identified from 2000-01-01 to 2012-12-31, was collected from the Cancer Hospital of the Chinese Academy of Medical Sciences. Relative frequencies (RF) were estimated for major histological subtypes and compared according to the years of diagnosis and birth.
Results The RF of adenocarcinoma (ADC) increased from 21.96% to 43.36% and the RF of squamous cell carcinoma (SCC) decreased from 39.11% to 32.23% from 2000 to 2012 in the 15 427 male lung cancer patients included in this study (Z=17.909, P<0.0001; Z=-6.117, P<0.0001). The RF of ADC increased from 28.72% in 2000-2004, 36.88% in 2005-2008 to 48.61% in 2009-2012 in patients born after 1960. The age-adjusted RF of ADC in 2007-2012 increased consistently in all the investigated areas.
Conclusion The increased RF of ADC in male lung cancer patients highlights the need for further investigation of the etiologic factors of these tumors. Smoke-free policies rather than modifying tobacco products should be enforced.

Citation: