Dietary Exposure to Benzyl Butyl Phthalate in China

ZHANG Lei; JIANG Ding Guo; SUI Hai Xia; WU Ping Gu; LIU Ai Dong; YANG Da Jin; LIU Zhao Ping; SONG Yan; LI Ning

doi:10.3967/bes2016.047

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Volume 29 Issue 5

May 2016

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Article Navigation > Biomedical and Environmental Sciences > 2016 > 29(5): 365-373

ZHANG Lei, JIANG Ding Guo, SUI Hai Xia, WU Ping Gu, LIU Ai Dong, YANG Da Jin, LIU Zhao Ping, SONG Yan, LI Ning. Dietary Exposure to Benzyl Butyl Phthalate in China[J]. Biomedical and Environmental Sciences, 2016, 29(5): 365-373. doi: 10.3967/bes2016.047

Citation:

ZHANG Lei, JIANG Ding Guo, SUI Hai Xia, WU Ping Gu, LIU Ai Dong, YANG Da Jin, LIU Zhao Ping, SONG Yan, LI Ning. Dietary Exposure to Benzyl Butyl Phthalate in China[J]. Biomedical and Environmental Sciences, 2016, 29(5): 365-373. doi: 10.3967/bes2016.047

Dietary Exposure to Benzyl Butyl Phthalate in China

doi: 10.3967/bes2016.047

Key Laboratory of Food Safety Risk Assessment, NationalHealth and Family Planning Commission of the People’s Republic of China China National Center for Food Safety Risk Assessment, Beijing 100022, China
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, Zhejiang, China

Funds: This work was partialy supported by China's Ministry ofScience & Technology (2014ZX09304307)

Abstract

ObjectiveBenzyl butyl phthalate (BBP) is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population.
MethodsThe BBP contents were detected in 7409 food samples from 25 foodcategories by gas chromatography-mass spectrometry operated in selected ion monitoring (SIM) mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake (TDI) of BBP established by European Food safety Agency.
ResultsIt was found that BBP was undetectable in most samples and the highest level was 1.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged≥2 years was
1.03 μg/kgbw perday and the highest average exposure was found in 2-6 years old children (1.98 μg/kg bw perday). The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake (TDI) in worst scenario.
ConclusionThe health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.
- Benzyl butyl phthalate,
- Dietary exposure,
- Risk assessment,
- China
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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Dietary Exposure to Benzyl Butyl Phthalate in China

doi: 10.3967/bes2016.047

Key Laboratory of Food Safety Risk Assessment, NationalHealth and Family Planning Commission of the People’s Republic of China China National Center for Food Safety Risk Assessment, Beijing 100022, China

Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, Zhejiang, China

Funds: This work was partialy supported by China's Ministry ofScience & Technology (2014ZX09304307)

Key words:

Abstract: ObjectiveBenzyl butyl phthalate (BBP) is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population.
MethodsThe BBP contents were detected in 7409 food samples from 25 foodcategories by gas chromatography-mass spectrometry operated in selected ion monitoring (SIM) mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake (TDI) of BBP established by European Food safety Agency.
ResultsIt was found that BBP was undetectable in most samples and the highest level was 1.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged≥2 years was
1.03 μg/kgbw perday and the highest average exposure was found in 2-6 years old children (1.98 μg/kg bw perday). The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake (TDI) in worst scenario.
ConclusionThe health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.

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