Volume 21 Issue 2
Apr.  2008
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SOO YEON KIM, SUN YOON, SOO MI KWON, KYE SOOK PARK, YANG CHA LEE-KIM. Kale Juice Improves Coronary Artery Disease Risk Factors in Hypercjlolesterolemiic Men[J]. Biomedical and Environmental Sciences, 2008, 21(2): 91-97.
Citation: SOO YEON KIM, SUN YOON, SOO MI KWON, KYE SOOK PARK, YANG CHA LEE-KIM. Kale Juice Improves Coronary Artery Disease Risk Factors in Hypercjlolesterolemiic Men[J]. Biomedical and Environmental Sciences, 2008, 21(2): 91-97.

Kale Juice Improves Coronary Artery Disease Risk Factors in Hypercjlolesterolemiic Men

Funds:  the Brain Korea 21 Project from the Korea Research Foundation
  • Objective To evaluate the effect of 3-month kale(Brassica oleracea acephala)iuice supplementation on coronary artery disease risk factors among hypercholesterolemic men.Methods Thkty-two men with hypercholesterolemia (>200 mg/dL)were recruited after annual health examinations among the faculty and staff at university.The subijects consumed 150 mL of kale iuice per day for a 12-week intervention period.Dietary and anthropomeu-ic assessments were performed and blood samples were collected to evaluate biochemical profdes before and after supplementation.Results Serum concentrations of HDL-cholesterol,and HDL-to LDL-cholesterol ratio were significantly increased by 27%(P<0.0001)and 52%(P<0.0001),respectively.The LDL-cholesterol concentration and the atherogenic index were significantly reduced by 1O%(P=0.O007)and 24.2%(P<0.0001),respectively without affecting body mass index,waist and hip circumferences,or nutrient intakes after three months of supplementation.While there was no difference in the concentration of malondialdehvde,significant increase in glutathione peroxidase activity(P=0.0005)were accompanied by a significant increase in the serom selenium level(P=0.0132).It was also foand that the responses of these risk factors to kale inice administration were dependent on smoking status.Conelusion Regular meals supplementation with kale juice can favorably influence serum lipid profiles and antioxidant systems.and hence contribute to reduce the risks of coronary artery disease in male subjects with hyperlipidemia.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Kale Juice Improves Coronary Artery Disease Risk Factors in Hypercjlolesterolemiic Men

Funds:  the Brain Korea 21 Project from the Korea Research Foundation

Abstract: Objective To evaluate the effect of 3-month kale(Brassica oleracea acephala)iuice supplementation on coronary artery disease risk factors among hypercholesterolemic men.Methods Thkty-two men with hypercholesterolemia (>200 mg/dL)were recruited after annual health examinations among the faculty and staff at university.The subijects consumed 150 mL of kale iuice per day for a 12-week intervention period.Dietary and anthropomeu-ic assessments were performed and blood samples were collected to evaluate biochemical profdes before and after supplementation.Results Serum concentrations of HDL-cholesterol,and HDL-to LDL-cholesterol ratio were significantly increased by 27%(P<0.0001)and 52%(P<0.0001),respectively.The LDL-cholesterol concentration and the atherogenic index were significantly reduced by 1O%(P=0.O007)and 24.2%(P<0.0001),respectively without affecting body mass index,waist and hip circumferences,or nutrient intakes after three months of supplementation.While there was no difference in the concentration of malondialdehvde,significant increase in glutathione peroxidase activity(P=0.0005)were accompanied by a significant increase in the serom selenium level(P=0.0132).It was also foand that the responses of these risk factors to kale inice administration were dependent on smoking status.Conelusion Regular meals supplementation with kale juice can favorably influence serum lipid profiles and antioxidant systems.and hence contribute to reduce the risks of coronary artery disease in male subjects with hyperlipidemia.

SOO YEON KIM, SUN YOON, SOO MI KWON, KYE SOOK PARK, YANG CHA LEE-KIM. Kale Juice Improves Coronary Artery Disease Risk Factors in Hypercjlolesterolemiic Men[J]. Biomedical and Environmental Sciences, 2008, 21(2): 91-97.
Citation: SOO YEON KIM, SUN YOON, SOO MI KWON, KYE SOOK PARK, YANG CHA LEE-KIM. Kale Juice Improves Coronary Artery Disease Risk Factors in Hypercjlolesterolemiic Men[J]. Biomedical and Environmental Sciences, 2008, 21(2): 91-97.

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