ZHAO Zhi Jun; LI Qiang; ZHOU Xin; MA Li; XU Li Qing; YANG Pei Zhen; MENG Xian Ya

doi:10.3967/bes2016.029

A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China

ZHAO Zhi Jun, LI Qiang, ZHOU Xin, MA Li, XU Li Qing, YANG Pei Zhen, MENG Xian Ya

文章导航 > Biomedical and Environmental Sciences > 2016 > 29(3): 229-232

ZHAO Zhi Jun, LI Qiang, ZHOU Xin, MA Li, XU Li Qing, YANG Pei Zhen, MENG Xian Ya. A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China[J]. Biomedical and Environmental Sciences, 2016, 29(3): 229-232. doi: 10.3967/bes2016.029

Citation:

ZHAO Zhi Jun, LI Qiang, ZHOU Xin, MA Li, XU Li Qing, YANG Pei Zhen, MENG Xian Ya. A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China[J]. Biomedical and Environmental Sciences, 2016, 29(3): 229-232. doi: 10.3967/bes2016.029

doi: 10.3967/bes2016.029

基金项目: This study was supported by the National Natural Scientific Foundation of China (30972556)

A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China

Qinghai Institute for Endemic Disease Prevention and Control, Xining 811602, Qinghai, China

Funds: This study was supported by the National Natural Scientific Foundation of China (30972556)

摘要: Brucellosis is one of the most widespread zoonotic diseases, with the most frequent complication being osteoarticular changes.The aim of this study was to assess the changes of C-terminal telopeptide of type Ⅱcollagen (CTX-Ⅱ) in patients infected with brucellosis.A total of84 brucellosis patients and 43 volunteers were selected and divided into brucellosisvs. control groups. Serum samples were subjected to serological tests for brucellosis, and CTX-Ⅱlevels in all samples were measuredsimultaneously with ELISA.The results showed that serum CTX-Ⅱ levels inhuman brucellosis were higher than those of healthy controls, without a statistically significant difference, butserum CTX-Ⅱ levels in male patients were significantly higher thanthose of female patients (P<0.05).This finding could indicate the biological changes in the cartilage and bone in human brucellosis.

[1]	YANG Liu, WANG Shi Yu, JIANG Ting Ting, DENG Wen, CHANG Min, WU Shu Ling, CAO Wei Hua, LU Yao, SHEN Ge, LIU Ru Yu, GAO Yuan Jiao, XU Meng Jiao, HU Lei Ping, ZHANG Lu, XIE Yao, LI Ming Hui. Relationship between Phenotypic Changes of Dendritic Cell Subsets and the Onset of Plateau Phase during Intermittent Interferon Therapy in Patients with CHB . Biomedical and Environmental Sciences, 2024, 37(3): 303-314. doi: 10.3967/bes2024.033
[2]	ZHANG Wei Jia, ZHAO Jie Rong, YIN Qi Kai, LIU Sheng Hui, WANG Rui Chen, FU Shi Hong, LI Fan, HE Ying, NIE Kai, LIANG Guo Dong, XU Song Tao, YANG Guang, WANG Huan Yu. Serological Investigation into the Infected Genotypes of Patients with Japanese Encephalitis in the Coastal Provinces of China . Biomedical and Environmental Sciences, 2024, 37(): 1-11. doi: 10.3967/bes2024.078
[3]	WANG Xin, ZHANG Ting, TANG Wen Yi, HUANG Xin. Clinical Manifestations and Surgical Outcomes of Primary Rhegmatogenous Retinal Detachment in Patients < 30 Years of Age with High Myopia . Biomedical and Environmental Sciences, 2023, 36(7): 644-648. doi: 10.3967/bes2023.092
[4]	YANG Man Li, WANG Jing Ya, ZONG Xing Yu, GUAN Li, LI Hui Zhen, XIONG Yi Bai, LIU Yu Qin, LI Ting, JI Xin Yu, SHANG Xi Yu, ZHANG Hui Fang, GUO Yang, GONG Zhao Yuan, ZHANG Lei, TONG Lin, CHEN Ren Bo, FAN Yi Pin, QIN Jin, WANG Fang, LIN Gang, SHI Nan Nan, WANG Yan Ping, MA Yan. Treatment Outcomes in COVID-19 Patients with Brucellosis: Case Series in Heilongjiang and Systematic Review of Literature . Biomedical and Environmental Sciences, 2023, 36(10): 930-939. doi: 10.3967/bes2023.035
[5]	LI Qiang, ZHOU Xin, XUE Hong Mei, WANG Jian Ling, LI Ji Quan, ZHAO Yan Mei, CHAO Jie, CHEN Yang Yang, XU Li Qing, ZHAO Zhi Jun, WANG Li Hua. Changes in Urinary Metabolomics of Female Kashin-Beck Disease Patients in Qinghai-Tibet Plateau, China . Biomedical and Environmental Sciences, 2023, 36(6): 537-541. doi: 10.3967/bes2023.065
[6]	LI Ming Hui, LU Hui Hui, CHEN Qi Qi, LIN Yan Jie, ZENG Zhan, LU Yao, ZHANG Lu, DONG Jian Ping, YI Wei, XIE Yao. Changes in the Cytokine Profiles of Patients with Chronic Hepatitis B during Antiviral Therapy . Biomedical and Environmental Sciences, 2021, 34(6): 443-453. doi: 10.3967/bes2021.061
[7]	LI Qiang, ZHAO Zhi Jun. Prevalence of Brick Tea-type Fluorosis in Children Aged 8–12 Years in Qinghai Province, China . Biomedical and Environmental Sciences, 2021, 34(4): 334-336. doi: 10.3967/bes2021.044
[8]	SUN Ying, CAO Yang, LI Zi, BAI Tian, ZHANG Hong, HU Shi Xiong, LI Fang Cai, ZHAO Xiang, CHEN Yong Kun, LU Jian, LIU Li Qi, WANG Da Yan, SHU Yue Long, ZHOU Jian Fang. Cross-neutralizing Anti-hemagglutinin Antibodies Isolated from Patients Infected with Avian Influenza A (H5N1) Virus . Biomedical and Environmental Sciences, 2020, 33(2): 103-113. doi: 10.3967/bes2020.014
[9]	LIU Bao Hua, ZHAO Miao Miao, LIANG Zi, GAO Li Jun, GAO Fei, WU Qun Hong, HAO Yan Hua, NING Ning. Factors Associated with Field Epidemiology Investigation: A Cross-sectional Study in China . Biomedical and Environmental Sciences, 2019, 32(6): 454-458. doi: 10.3967/bes2019.060
[10]	LIU Gao Shan, LI Hong, ZHAO Sheng Cang, LU Rou Jian, NIU Pei Hua, TAN Wen Jie. Viral and Bacterial Etiology of Acute Febrile Respiratory Syndrome among Patients in Qinghai, China . Biomedical and Environmental Sciences, 2019, 32(6): 438-445. doi: 10.3967/bes2019.058
[11]	ZHAO Xiu Ying, ZENG Zhao Ying, HUA Wen Hao, YU Yan Hua, GUO Cai Ping, ZHAO Xiu Qin, DONG Hai Yan, LIU Jie, WAN Kang Lin. A Retrospective Study of Culture-confirmed Mycobacterial Infection among Hospitalized HIV-infected Patients in Beijing, China . Biomedical and Environmental Sciences, 2018, 31(6): 459-462. doi: 10.3967/bes2018.060
[12]	TAXITIEMUER Aierken, TUERDI Gulina, ZHANG Yi, WUSHOUER Fuerhati, TAO Xiao Yan, TALIPU Jiangatai, YIMAMU Tuohetiyaer, MA Hui Lai. An Investigation of the First Case of Human Rabies Caused by a Fox in China in May 2016 . Biomedical and Environmental Sciences, 2017, 30(11): 825-828. doi: 10.3967/bes2017.110
[13]	ZHAO Zhi Jun, PU Guang Lan, ZHAN Pei Zhen, LI Qiang, WU Chun Ning, WANG Li Hua. Detection of the Urinary Biomarkers PYD, CTX-Ⅱ, and DPD in Patients with Kashin-Beck Disease in the Qinghai Province of China . Biomedical and Environmental Sciences, 2017, 30(5): 380-383. doi: 10.3967/bes2017.050
[14]	WANG Sheng Fen, ZHOU Yang, PANG Yu, ZHENG Hui Wen, ZHAO Yan Lin. Prevalence and Risk Factors of Primary Drug-Resistant Tuberculosis in China . Biomedical and Environmental Sciences, 2016, 29(2): 91-98. doi: 10.3967/bes2016.010
[15]	LI Jun Jian, LI Wei, XU Guang Rong, XU Ke Jun, YE Ping, QUAN Yu, NING Rong Bing, GAO Hai Jun, HE Qian Jun, ZHOU Ying, WU Wei Ping. Analysis on Serum Trace Element Levels of Echinococciasis Patients in Garze Tibetan Autonomous Prefecture in Sichuan, China, 2011 . Biomedical and Environmental Sciences, 2015, 28(9): 683-686. doi: 10.3967/bes2015.096
[16]	LIU Jie, WANG Hui Zhu, LIAN Lu Lu, YU Yan Hua, ZHAO Xiu Qin, GUO Cai Ping, LIU Hai Can, LIU Shu Mei, ZHAO Hui, ZENG Zhao Ying, ZHAO Xiu Ying, WAN Kang Lin. Molecular Characteristics and Drug Susceptibility of Mycobacterium tuberculosis Isolates from Patients Co-infected with Human Immunodeficiency Virus in Beijing, China . Biomedical and Environmental Sciences, 2015, 28(3): 222-226. doi: 10.3967/bes2015.030
[17]	RAO Hua Xiang, YU Juan, GUO Peng, MA Yong Cheng, MA Zhong Wen, GE Hua, WANG Chun Xiang, SHI Yan. Bartonella Species Detected in the Plateau Pikas (Ochotona curzoiae) from Qinghai Plateau in China . Biomedical and Environmental Sciences, 2015, 28(9): 674-678. doi: 10.3967/bes2015.094
[18]	DU Xiang, WANG Jin, YANG Chun Yong, ZHOU Xian Feng, CHEN Wei, CAO Xing Jiang, ZHOU Yuan Yuan, YU Ning Le. Investigation of Mean Glandular Dose in Diagnostic Mammography in China . Biomedical and Environmental Sciences, 2014, 27(5): 396-399. doi: 10.3967/bes2014.067
[19]	DING Guo Wei, HSI Jenny H, LIU Hui Xin, SU Ying Ying, WANG Jun Jie, BAI Jun, WANG Gui Xiang, WANG Hai Bo, DONG Rui Ling, WANG Ning. HIV-infected Female Sex Workers High Risk Behavior and Attitude Changes in Kaiyuan City, Yunnan Province, China . Biomedical and Environmental Sciences, 2014, 27(6): 444-452. doi: 10.3967/bes2014.073
[20]	FA-XIN HEI, HAI-LI TANG, Kun-Xue Hong, Jian-Ping Chen, HONG PENG, LIN YUAN, JIANG-QING XU, Yi-Ming Shao. Association of Neutralization Sensitivity of HIV- 1 Primary Isolates With Biological Properties of Isolates From HIV-1 Infected Chinese Individuals . Biomedical and Environmental Sciences, 2005, 18(2): 128-136.

点击查看大图

计量

文章访问数: 754
HTML全文浏览量: 211
PDF下载量: 38
被引次数: 0

A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China

doi: 10.3967/bes2016.029

基金项目: This study was supported by the National Natural Scientific Foundation of China (30972556)

刊出日期: 2016-03-20

摘要: Brucellosis is one of the most widespread zoonotic diseases, with the most frequent complication being osteoarticular changes.The aim of this study was to assess the changes of C-terminal telopeptide of type Ⅱcollagen (CTX-Ⅱ) in patients infected with brucellosis.A total of84 brucellosis patients and 43 volunteers were selected and divided into brucellosisvs. control groups. Serum samples were subjected to serological tests for brucellosis, and CTX-Ⅱlevels in all samples were measuredsimultaneously with ELISA.The results showed that serum CTX-Ⅱ levels inhuman brucellosis were higher than those of healthy controls, without a statistically significant difference, butserum CTX-Ⅱ levels in male patients were significantly higher thanthose of female patients (P<0.05).This finding could indicate the biological changes in the cartilage and bone in human brucellosis.

English Abstract

Citation:

ZHAO Zhi Jun, LI Qiang, ZHOU Xin, MA Li, XU Li Qing, YANG Pei Zhen, MENG Xian Ya. A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China[J]. Biomedical and Environmental Sciences, 2016, 29(3): 229-232. doi: 10.3967/bes2016.029

全文HTML

下载: 全尺寸图片幻灯片

返回文章

用微信扫码二维码

分享至好友和朋友圈

Biomedical and Environmental Sciences ISSN 0895-3988 CN 11-2816 / Q

Publish Under the Auspices of Chinese Center for Disease Control and Prevention

Distributed by Chinese Center for Disease Control and Prevention

Quick Links

Supported by Beijing Renhe Information Technology Co. Ltd E-mail: info@rhhz.net

doi: 10.3967/bes2016.029

A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China

计量

出版历程

A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China

doi: 10.3967/bes2016.029

English Abstract

A Primary Investigation on Serum CTX-Ⅱ Changes in Patients Infected with Brucellosis in Qinghai Plateau, China

Qinghai Institute for Endemic Disease Prevention and Control, Xining 811602, Qinghai, China

全文HTML

目录