CHEN Yu Qiao; CHEN Chao; ZHANG Xiao Jian; ZHENG Qi; LIU Yuan Yuan

doi:10.3967/0895-3988.2012.02.016

Inactivation of Resistant Mycobacteria mucogenicum in Water: Chlorine Resistance and Mechanism Analysis*

CHEN Yu Qiao, CHEN Chao, ZHANG Xiao Jian, ZHENG Qi, LIU Yuan Yuan

文章导航 > Biomedical and Environmental Sciences > 2012 > 25(2): 230-237

CHEN Yu Qiao, CHEN Chao, ZHANG Xiao Jian, ZHENG Qi, LIU Yuan Yuan. Inactivation of Resistant Mycobacteria mucogenicum in Water: Chlorine Resistance and Mechanism Analysis*[J]. Biomedical and Environmental Sciences, 2012, 25(2): 230-237. doi: 10.3967/0895-3988.2012.02.016

Citation:

CHEN Yu Qiao, CHEN Chao, ZHANG Xiao Jian, ZHENG Qi, LIU Yuan Yuan. Inactivation of Resistant Mycobacteria mucogenicum in Water: Chlorine Resistance and Mechanism Analysis*[J]. Biomedical and Environmental Sciences, 2012, 25(2): 230-237. doi: 10.3967/0895-3988.2012.02.016

doi: 10.3967/0895-3988.2012.02.016

基金项目: the Major Science and Technology Program for Water Pollution Control and Treatment(2008ZX07420-005)%National Natural Science Foundation of China(50708050)

Inactivation of Resistant Mycobacteria mucogenicum in Water: Chlorine Resistance and Mechanism Analysis*

School of Environment, Tsinghua University, Beijing 100084, China

Funds: the Major Science and Technology Program for Water Pollution Control and Treatment(2008ZX07420-005)%National Natural Science Foundation of China(50708050)

摘要: Objective To better understand the mechanism of chlorine resistance of mycobacteria and evaluate the efficiency of various disinfection processes.Methods Inactivation experiments of one strain Mycobacteria mucogenicum,isolated from a drinking water distribution system in South China were conducted with various chlorine disinfectants.Inactivation efficiency and disinfectant residual,as well as the formation of organic chloramines,were measured during the experiments.Results This strain of M.mucogenicum showed high resistance to chlorine.The CT values of 99.9％ inactivation by free chlorine,monochloramine and chlorine dioxide were detected as 29.6±1.46,170±6.16,and 10.9±1.55 min·(mg/L) respectively,indicating that chlorine dioxide exhibited significantly higher efficiency than free chlorine and monochloramine.It was also found that M.mucogenicum reacted with chlorine disinfectants more slowly than S.aureus,but consumed more chlorine disinfectants during longer time of contact.Lipid analysis of the cell construction revealed that 95.7％ of cell membrane lipid of M.mucogenicum was composed of saturated long chain fatty acids.Saturated fatty acids were regarded as more stable and more hydrophilic which enabled the cell membrane to prevent the diffusion of chlorine.Conclusion It was concluded that different compositions of cell membrane might endow M.mucogenicum with a higher chlorine resistance.
- /
- /
- /
- /
Abstract: Objective To better understand the mechanism of chlorine resistance of mycobacteria and evaluate the efficiency of various disinfection processes.Methods Inactivation experiments of one strain Mycobacteria mucogenicum,isolated from a drinking water distribution system in South China were conducted with various chlorine disinfectants.Inactivation efficiency and disinfectant residual,as well as the formation of organic chloramines,were measured during the experiments.Results This strain of M.mucogenicum showed high resistance to chlorine.The CT values of 99.9％ inactivation by free chlorine,monochloramine and chlorine dioxide were detected as 29.6±1.46,170±6.16,and 10.9±1.55 min·(mg/L) respectively,indicating that chlorine dioxide exhibited significantly higher efficiency than free chlorine and monochloramine.It was also found that M.mucogenicum reacted with chlorine disinfectants more slowly than S.aureus,but consumed more chlorine disinfectants during longer time of contact.Lipid analysis of the cell construction revealed that 95.7％ of cell membrane lipid of M.mucogenicum was composed of saturated long chain fatty acids.Saturated fatty acids were regarded as more stable and more hydrophilic which enabled the cell membrane to prevent the diffusion of chlorine.Conclusion It was concluded that different compositions of cell membrane might endow M.mucogenicum with a higher chlorine resistance.
- Chlorine inactivation /
- Chlorine consumption /
- Lipid assay /
- Mechanism /
- M. mucogenicum

[1]	Fang Xue, Wenchao Chen, Xia Lian, Guanghui He, Jingyuan Tian, Yinghong Liu, Gaiqing Wang. The Regulatory Role and Mechanism of Circadian Rhythm in Hemoglobin Co-cultured Neurovascular Unit . Biomedical and Environmental Sciences, 2024, 37(7): 726-738. doi: 10.3967/bes2024.090
[2]	JI Xiao Ning, LIU Zhao Ping, ZHANG Chao Zheng, CHEN Min, LIANG Jiang, LU Jiang, ZHANG Lei. The Effect and Mechanism of Fructus lycii on Improvement of Exercise Fatigue Using a Network Pharmacological Approach with in vitro Experimental Verification . Biomedical and Environmental Sciences, 2024, 37(1): 42-53. doi: 10.3967/bes2024.005
[3]	LIU Xiao, CAO Ying, LIN Xiao Wan, GAO Dan Yang, MIAO Hui Hui, LI Tian Zuo. Metabolomic Analysis in Saliva and Different Brain Regions of Older Mice with Postoperative Delirium Behaviors . Biomedical and Environmental Sciences, 2024, 37(2): 133-145. doi: 10.3967/bes2024.015
[4]	ZHANG Xiao Li, YU Sheng Nan, QU Ruo Di, ZHAO Qiu Yi, PAN Wei Zhe, CHEN Xu Shen, ZHANG Qian, LIU Yan, LI Jia, GAO Yi, LYU Yi, YAN Xiao Yan, LI Ben, REN Xue Feng, QIU Yu Lan. Mechanism of Learning and Memory Impairment in Rats Exposed to Arsenic and/or Fluoride Based on Microbiome and Metabolome . Biomedical and Environmental Sciences, 2023, 36(3): 253-268. doi: 10.3967/bes2023.028
[5]	XIAO Shi Qi, XU Da, DUAN Hong Yang, FAN Xue Ting, LI Gui Lian, ZHANG Wen, LI Ma Chao, HAN Na, LI Xin Yao, LI Na, ZHAO Li lan, ZHAO Xiu Qin, WAN Kang Lin, LIU Hai Can, FENG Wen Hai. Immunogenicity of Whole Mycobacterium intracellulare Proteins and Fingding on the Cross-Reactive Proteins between M. intracellulare and M. tuberculosis . Biomedical and Environmental Sciences, 2021, 34(7): 528-539. doi: 10.3967/bes2021.073
[6]	ZHAO Hong, QIU Ting Ting, LIU Mei Qing, CHEN Lin Xi. SENP2: A Novel Regulatory Mechanism of Brown Adipocyte Differentiation . Biomedical and Environmental Sciences, 2020, 33(11): 872-876. doi: 10.3967/bes2020.119
[7]	JIANG Han Ji, CHEN Na, SHEN Zhi Qiang, YIN Jing, QIU Zhi Gang, MIAO Jing, YANG Zhong Wei, SHI Dan Yang, WANG Hua Ran, WANG Xin Wei, LI Jun Wen, YANG Dong, JIN Min. Inactivation of Poliovirus by Ozone and the Impact of Ozone on the Viral Genome . Biomedical and Environmental Sciences, 2019, 32(5): 324-333. doi: 10.3967/bes2019.044
[8]	WU Xuan, WU Tong, LI Ke, LI Yuan, HU Ting Ting, WANG Wei Feng, QIANG Su Jing, XUE Shao Bo, LIU Wei Wei. The Mechanism and Influence of AKAP12 in Different Cancers . Biomedical and Environmental Sciences, 2018, 31(12): 927-932. doi: 10.3967/bes2018.127
[9]	TAN Dong Mei, LYU Su Ling, LIU Wei, ZENG Xian Ying, LAN Lan, QU Cong, ZHUGE Shi Yang, ZHONG Yan Xu, XIE Yi Hong, LI Xiu Gui. Utility of Droplet Digital PCR Assay for Quantitative Detection of Norovirus in Shellfish, from Production to Consumption in Guangxi, China . Biomedical and Environmental Sciences, 2018, 31(10): 713-720. doi: 10.3967/bes2018.096
[10]	SONG Quan Quan, NIU Jing Ping, ZHANG Shu Yu, LIANG Ting Ting, ZHOU Ji, FENG Shan Shan. Effects of Simulated Heat Wave and Ozone on High Fat Diet ApoE Deficient Mice . Biomedical and Environmental Sciences, 2018, 31(10): 757-768. doi: 10.3967/bes2018.101
[11]	LIU Xin, GONG Wei, XU Yan Qiong, ZHU Bao Li. Dimethylacetamide-induced Hepatic Injuryin Vitro:Mechanism and Potential Preventive Strategy . Biomedical and Environmental Sciences, 2016, 29(2): 153-157. doi: 10.3967/bes2016.018
[12]	WU Li Li, JIA Bao Hui, SUN Jian, CHEN Jun Xi, LIU Zhong Ying, LIU Yuan. Protective Effects of Ginsenoside Rb1 on Septic Rats and Its Mechanism . Biomedical and Environmental Sciences, 2014, 27(4): 300-303. doi: 10.3967/bes2014.053
[13]	LI Tian Zhi, YUAN Ming, CHEN Zhen Hong, GUO Ying Hua, KANG Chun Yan, WANG Jing Yu, LI Zhi Li, WANG De Sheng, WANG Hui Juan, YUAN Min, LIU Chang Ting. Effect of Simulated Microgravity and its Associated Mechanism on Pulmonary Circulation in Rats . Biomedical and Environmental Sciences, 2013, 26(2): 118-127. doi: 10.3967/0895-3988.2013.02.006
[14]	BAI Ya Na, MA Li, WANG Qiu Ying, PU Hong Quan, ZHANG Xiao Pei, WU Xi Jiang, XUAN Xiao Qiang. The Mechanism of Acute Lung Injury Induced by Nickel Carbonyl in Rats . Biomedical and Environmental Sciences, 2013, 26(7): 625-628. doi: 10.3967/0895-3988.2013.07.018
[15]	QIAO Rong, HUANG ChengYu, DU HuiZhang, ZENG Guo, LI Ling, YE Sheng. Milk Consumption and Lactose Intolerance in Adults . Biomedical and Environmental Sciences, 2011, 24(5): 512-517. doi: 10.3967/0895-3988.2011.05.009
[16]	MENG Xiu Hong, TAO Fang Biao, WAN Yu Hui, HU Yan, WANG Ren Xi. Coping as a Mechanism Linking Stressful Life Events and Mental Health Problems in Adolescents . Biomedical and Environmental Sciences, 2011, 24(6): 649-655. doi: 10.3967/0895-3988.2011.06.009
[17]	MIN ZHU, LI-SHI ZHANG, XIAO-FANG PEI, XIN XU. Preparation and Evaluation of Novel Solid Chlorine Dioxide-based Disinfectant Powder in Single-pack . Biomedical and Environmental Sciences, 2008, 21(2): 157-162.
[18]	GUI-DONG DAI, LUN-BIAO CUI, LING SONG, REN-ZHEN ZHAO, JIAN-FENG CHENG, MEI-XIA LIU, JIAN-WEI ZHOU, HANG XIAO, XIN-RU WANG. Induction of Bladder Lesion by Terephthalic Acid and Its Mechanism . Biomedical and Environmental Sciences, 2005, 18(4): 211-219.
[19]	GUO-QING WANG, CHAO-WU ZHANG, HENG-CHUAN LIU, ZHAO-BIN CHEN. Comparison of Susceptibilities of M. tuberculosis H37Ra and M. chelonei subsp. Abscessus to Disinfectants . Biomedical and Environmental Sciences, 2005, 18(2): 124-127.
[20]	TANG XIAO-JIANG, LAI GUAN-CHAO, HUANG Jian-xun, LI LAI-YU, DENG YING-YU, YUE Fei, ZHANG QING. Studies on Hypokalemia Induced by Trimethyltin Chloride . Biomedical and Environmental Sciences, 2002, 15(1): 16-24.

点击查看大图

计量

文章访问数: 1437
HTML全文浏览量: 332
PDF下载量: 74
被引次数: 0

Inactivation of Resistant Mycobacteria mucogenicum in Water: Chlorine Resistance and Mechanism Analysis*

doi: 10.3967/0895-3988.2012.02.016

基金项目: the Major Science and Technology Program for Water Pollution Control and Treatment(2008ZX07420-005)%National Natural Science Foundation of China(50708050)

刊出日期: 2012-04-20

关键词:

Chlorine inactivation /

Chlorine consumption /

Lipid assay /

Mechanism /

M. mucogenicum

摘要: Objective To better understand the mechanism of chlorine resistance of mycobacteria and evaluate the efficiency of various disinfection processes.Methods Inactivation experiments of one strain Mycobacteria mucogenicum,isolated from a drinking water distribution system in South China were conducted with various chlorine disinfectants.Inactivation efficiency and disinfectant residual,as well as the formation of organic chloramines,were measured during the experiments.Results This strain of M.mucogenicum showed high resistance to chlorine.The CT values of 99.9％ inactivation by free chlorine,monochloramine and chlorine dioxide were detected as 29.6±1.46,170±6.16,and 10.9±1.55 min·(mg/L) respectively,indicating that chlorine dioxide exhibited significantly higher efficiency than free chlorine and monochloramine.It was also found that M.mucogenicum reacted with chlorine disinfectants more slowly than S.aureus,but consumed more chlorine disinfectants during longer time of contact.Lipid analysis of the cell construction revealed that 95.7％ of cell membrane lipid of M.mucogenicum was composed of saturated long chain fatty acids.Saturated fatty acids were regarded as more stable and more hydrophilic which enabled the cell membrane to prevent the diffusion of chlorine.Conclusion It was concluded that different compositions of cell membrane might endow M.mucogenicum with a higher chlorine resistance.

English Abstract

Inactivation of Resistant Mycobacteria mucogenicum in Water: Chlorine Resistance and Mechanism Analysis*

School of Environment, Tsinghua University, Beijing 100084, China

Funds: the Major Science and Technology Program for Water Pollution Control and Treatment(2008ZX07420-005)%National Natural Science Foundation of China(50708050)

Publish Date: 2012-04-20

Keywords:

Abstract: Objective To better understand the mechanism of chlorine resistance of mycobacteria and evaluate the efficiency of various disinfection processes.Methods Inactivation experiments of one strain Mycobacteria mucogenicum,isolated from a drinking water distribution system in South China were conducted with various chlorine disinfectants.Inactivation efficiency and disinfectant residual,as well as the formation of organic chloramines,were measured during the experiments.Results This strain of M.mucogenicum showed high resistance to chlorine.The CT values of 99.9％ inactivation by free chlorine,monochloramine and chlorine dioxide were detected as 29.6±1.46,170±6.16,and 10.9±1.55 min·(mg/L) respectively,indicating that chlorine dioxide exhibited significantly higher efficiency than free chlorine and monochloramine.It was also found that M.mucogenicum reacted with chlorine disinfectants more slowly than S.aureus,but consumed more chlorine disinfectants during longer time of contact.Lipid analysis of the cell construction revealed that 95.7％ of cell membrane lipid of M.mucogenicum was composed of saturated long chain fatty acids.Saturated fatty acids were regarded as more stable and more hydrophilic which enabled the cell membrane to prevent the diffusion of chlorine.Conclusion It was concluded that different compositions of cell membrane might endow M.mucogenicum with a higher chlorine resistance.

Citation:

CHEN Yu Qiao, CHEN Chao, ZHANG Xiao Jian, ZHENG Qi, LIU Yuan Yuan. Inactivation of Resistant Mycobacteria mucogenicum in Water: Chlorine Resistance and Mechanism Analysis*[J]. Biomedical and Environmental Sciences, 2012, 25(2): 230-237. doi: 10.3967/0895-3988.2012.02.016