PANG Hui; TONG Jing; LIU Hai Can; DU Yang Guang; ZHAO Xiu Qin; JIANG Yi; WU Xiao Cui

doi:10.3967/bes2014.136

Molecular Characterization and Drug-resistance of Mycobacterium tuberculosis Strains in Xuzhou, China

PANG Hui, TONG Jing, LIU Hai Can, DU Yang Guang, ZHAO Xiu Qin, JIANG Yi, WU Xiao Cui

文章导航 > Biomedical and Environmental Sciences > 2014 > 27(12): 960-964

PANG Hui, TONG Jing, LIU Hai Can, DU Yang Guang, ZHAO Xiu Qin, JIANG Yi, WU Xiao Cui. Molecular Characterization and Drug-resistance of Mycobacterium tuberculosis Strains in Xuzhou, China[J]. Biomedical and Environmental Sciences, 2014, 27(12): 960-964. doi: 10.3967/bes2014.136

Citation:

PANG Hui, TONG Jing, LIU Hai Can, DU Yang Guang, ZHAO Xiu Qin, JIANG Yi, WU Xiao Cui. Molecular Characterization and Drug-resistance of Mycobacterium tuberculosis Strains in Xuzhou, China[J]. Biomedical and Environmental Sciences, 2014, 27(12): 960-964. doi: 10.3967/bes2014.136

doi: 10.3967/bes2014.136

基金项目: This work was funded by the projects 2013ZX10003002-001 of Chinese National Key Program of Mega Infectious Disease of the National 12th Five-Year Plan and the Science and Technology Innovation Team Support project CX201412 of Changzhi Medical College

Molecular Characterization and Drug-resistance of Mycobacterium tuberculosis Strains in Xuzhou, China

Department of Immunology, Changzhi Medical College, Changzhi 046000, Shanxi, China; State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Department of Immunology, Xiangya School of Medicine, Central south University, Changsha 410078, Hunan, China
Xuzhou Municipal Centre for Disease Control and Prevention, Xuzhou 221006, Jiangsu, China
State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,Hangzhou 310000, Zhejiang, China

Funds: This work was funded by the projects 2013ZX10003002-001 of Chinese National Key Program of Mega Infectious Disease of the National 12th Five-Year Plan and the Science and Technology Innovation Team Support project CX201412 of Changzhi Medical College

摘要: To understand the genetic diversity and drug resistance status of Mycobacterium tuberculosis (M.tuberculosis) circulating in Xuzhou of China,the spacer-oligonucleotide typing (Spoligotyping) and multi-loci VNTRs (variable number tandem repeats) analysis (MLVA) were utilized for the genotyping of the isolates.Drug susceptibility test (DST) was performed by the proportion method on the Lowenstein-Jensen (L-J) medium using isoniazid,rifampicin,ethambutol,and streptomycin.
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- Mycobacterium tuberculosis /
- susceptibility test /
- genetic diversity /
- drug resistance

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Molecular Characterization and Drug-resistance of Mycobacterium tuberculosis Strains in Xuzhou, China

doi: 10.3967/bes2014.136

刊出日期: 2014-12-20

关键词:

Mycobacterium tuberculosis /

susceptibility test /

genetic diversity /

drug resistance

摘要: To understand the genetic diversity and drug resistance status of Mycobacterium tuberculosis (M.tuberculosis) circulating in Xuzhou of China,the spacer-oligonucleotide typing (Spoligotyping) and multi-loci VNTRs (variable number tandem repeats) analysis (MLVA) were utilized for the genotyping of the isolates.Drug susceptibility test (DST) was performed by the proportion method on the Lowenstein-Jensen (L-J) medium using isoniazid,rifampicin,ethambutol,and streptomycin.

English Abstract

Citation:

PANG Hui, TONG Jing, LIU Hai Can, DU Yang Guang, ZHAO Xiu Qin, JIANG Yi, WU Xiao Cui. Molecular Characterization and Drug-resistance of Mycobacterium tuberculosis Strains in Xuzhou, China[J]. Biomedical and Environmental Sciences, 2014, 27(12): 960-964. doi: 10.3967/bes2014.136