YIN Xue Yao; ZHENG Fen Ping; ZHOU Jia Qiang; DU Ying; PAN Qian Qian; ZHANG Sai Fei; YU Dan; LI Hong

doi:10.3967/bes2014.059

doi: 10.3967/bes2014.059

基金项目: The study was supported by the Major Science and Technology Project of Zhejiang Province(Grant 2009C03010-4)%the National Key Technology R&D Program of China(Grants 2012BAI02B03 and 2009BAI80B00)

Central Obesity and Metabolic Risk Factors in Middle-aged Chinese

Department of Endocrinology, Sir Run Run Shaw Hospital, Affiliated to School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang, China

Funds: The study was supported by the Major Science and Technology Project of Zhejiang Province(Grant 2009C03010-4)%the National Key Technology R&D Program of China(Grants 2012BAI02B03 and 2009BAI80B00)

摘要: Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference (WC) has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese.
Methods The study involved 923 subjects aged 40-65 years. The metabolic risk factors were defined according to the Chinese Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and≥90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and≥85 cm were used as cut-off values of central pre-obesity and central obesity in females.
Results First, WC values corresponding to body mass index (BMI) 24 kg/m2 and visceral fat area (VFA) 80 cm2 were 88.55 cm and 88.51 cm in males, and 81.46 cm and 82.51 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females (81.75 cm). Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels.
Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.
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Abstract: Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference (WC) has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese.
Methods The study involved 923 subjects aged 40-65 years. The metabolic risk factors were defined according to the Chinese Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and≥90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and≥85 cm were used as cut-off values of central pre-obesity and central obesity in females.
Results First, WC values corresponding to body mass index (BMI) 24 kg/m2 and visceral fat area (VFA) 80 cm2 were 88.55 cm and 88.51 cm in males, and 81.46 cm and 82.51 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females (81.75 cm). Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels.
Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.
- Central obesity /
- Central pre-obesity /
- Metabolic syndrome /
- Middle-aged Chinese

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doi: 10.3967/bes2014.059

Central Obesity and Metabolic Risk Factors in Middle-aged Chinese

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Central Obesity and Metabolic Risk Factors in Middle-aged Chinese

doi: 10.3967/bes2014.059

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Central Obesity and Metabolic Risk Factors in Middle-aged Chinese

Department of Endocrinology, Sir Run Run Shaw Hospital, Affiliated to School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang, China

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doi: 10.3967/bes2014.059

Central Obesity and Metabolic Risk Factors in Middle-aged Chinese

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Central Obesity and Metabolic Risk Factors in Middle-aged Chinese

doi: 10.3967/bes2014.059

English Abstract

Central Obesity and Metabolic Risk Factors in Middle-aged Chinese

Department of Endocrinology, Sir Run Run Shaw Hospital, Affiliated to School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang, China

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