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This standard specifies the indicators, reference values, and measurement methods for vitamin D deficiency and insufficiency screening in the people.
This standard is applicable to the determination of vitamin D nutritional status in the people.
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The following documents are essential for the application of this document. For the references dated, only their dated versions are applies to this document; for the references undated, their latest versions, including all amendments, are applicable to this document.
GB/T 603 Chemical reagent Preparation of formulations and products used in test methods
GB/T 6682 Analysis of laboratory water specifications and test methods
WS/T 225 Collection and processing of blood samples for clinical chemical testing
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The following terms and definitions apply to this document.
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The main circulating form of vitamin D in the blood, with good stability, is recognized as a reliable indicator for evaluating the nutritional status of vitamin D in the human body. It mainly includes two forms: 25 (OH) D2 and 25 (OH) D3, of which 25 (OH) D3 is the main form of vitamin D present in the blood.
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Vitamin D deficiency can be determined when the content of 25-hydroxyvitamin D in human serum (or plasma) is lower than the reference values for deficiency.
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Vitamin D insufficiency can be determined when the content of 25-hydroxyvitamin D in human serum (or plasma) is lower than the reference values for the normal people, but higher than that for deficiency.
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Determination indicators and reference values for vitamin D nutritional status in the people are shown in Table 1.
Table 1. Determination indicators and reference values for vitamin D nutritional status in the people
Determination indicator Normal Insufficiency Deficiency Content of 25-hydroxyvitamin D
in serum (or plasma)ng/mL nmol/L ng/mL nmol/L ng/mL nmol/L ≥ 20 ≥ 50 ≥ 12 to < 20 ≥ 30 to < 50 < 12 < 30 -
Follow the methods specified in Appendix A.
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Follow the methods specified in Appendix B.
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Follow the methods specified in Appendix C.
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Follow the methods specified in Appendix D.
Method for Vitamin D Deficiency Screening
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Table 1. Determination indicators and reference values for vitamin D nutritional status in the people
Determination indicator Normal Insufficiency Deficiency Content of 25-hydroxyvitamin D
in serum (or plasma)ng/mL nmol/L ng/mL nmol/L ng/mL nmol/L ≥ 20 ≥ 50 ≥ 12 to < 20 ≥ 30 to < 50 < 12 < 30 
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- 网络出版日期: 2023-09-01
- 刊出日期: 2023-09-01
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