MA Ka Ying; LIANG Yin Tong; CHEN Jing Nan; JIANG Yue; KWAN Kin Ming; PENG Cheng; JIAO Rui; ZUO Yuan Yuan; HUANG Yu; CHEN Zhen Yu

doi:10.3967/0895-3988.2012.04.003

Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

MA Ka Ying, LIANG Yin Tong, CHEN Jing Nan, JIANG Yue, KWAN Kin Ming, PENG Cheng, JIAO Rui, ZUO Yuan Yuan, HUANG Yu, CHEN Zhen Yu

文章导航 > Biomedical and Environmental Sciences > 2012 > 25(4): 392-398

MA Ka Ying, LIANG Yin Tong, CHEN Jing Nan, JIANG Yue, KWAN Kin Ming, PENG Cheng, JIAO Rui, ZUO Yuan Yuan, HUANG Yu, CHEN Zhen Yu. Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet[J]. Biomedical and Environmental Sciences, 2012, 25(4): 392-398. doi: 10.3967/0895-3988.2012.04.003

Citation:

MA Ka Ying, LIANG Yin Tong, CHEN Jing Nan, JIANG Yue, KWAN Kin Ming, PENG Cheng, JIAO Rui, ZUO Yuan Yuan, HUANG Yu, CHEN Zhen Yu. Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet[J]. Biomedical and Environmental Sciences, 2012, 25(4): 392-398. doi: 10.3967/0895-3988.2012.04.003

doi: 10.3967/0895-3988.2012.04.003

基金项目: Hong Kong Research Grant Council(CUHK 4622/08M)

Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

Food & Nutritional Sciences Programme, School of Life Sciences, The Chinese University of Hong Kong, Shatin,NT, Hong Kong, China
Department of Biology and Kwong Living Trust Food Safety & Analysis Laboratory,Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China

Funds: Hong Kong Research Grant Council(CUHK 4622/08M)

摘要: Objective To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters.Methods Male,castrated,female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0,2,and 8 g calcium per kg diet for a period of six weeks.Changes in plasma lipoprotein profile were monitored at the end of week 0,3 and 6.Results Plasma total cholesterol (TC),non-high density lipoprotein cholesterol (non-HDL-C),triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters.In contrast,three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.Conclusion Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.
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Abstract: Objective To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters.Methods Male,castrated,female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0,2,and 8 g calcium per kg diet for a period of six weeks.Changes in plasma lipoprotein profile were monitored at the end of week 0,3 and 6.Results Plasma total cholesterol (TC),non-high density lipoprotein cholesterol (non-HDL-C),triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters.In contrast,three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.Conclusion Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.
- Calcium /
- Cholesterol /
- Triacylglycerols /
- Fecal sterols

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Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

doi: 10.3967/0895-3988.2012.04.003

基金项目: Hong Kong Research Grant Council(CUHK 4622/08M)

刊出日期: 2012-08-20

关键词:

Calcium /

Cholesterol /

Triacylglycerols /

Fecal sterols

摘要: Objective To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters.Methods Male,castrated,female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0,2,and 8 g calcium per kg diet for a period of six weeks.Changes in plasma lipoprotein profile were monitored at the end of week 0,3 and 6.Results Plasma total cholesterol (TC),non-high density lipoprotein cholesterol (non-HDL-C),triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters.In contrast,three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.Conclusion Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.

English Abstract

Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

Food & Nutritional Sciences Programme, School of Life Sciences, The Chinese University of Hong Kong, Shatin,NT, Hong Kong, China

Department of Biology and Kwong Living Trust Food Safety & Analysis Laboratory,Hong Kong Baptist University, Kowloon Tong, Hong Kong, China

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China

Funds: Hong Kong Research Grant Council(CUHK 4622/08M)

Publish Date: 2012-08-20

Keywords:

Abstract: Objective To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters.Methods Male,castrated,female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0,2,and 8 g calcium per kg diet for a period of six weeks.Changes in plasma lipoprotein profile were monitored at the end of week 0,3 and 6.Results Plasma total cholesterol (TC),non-high density lipoprotein cholesterol (non-HDL-C),triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters.In contrast,three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.Conclusion Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.

Citation:

MA Ka Ying, LIANG Yin Tong, CHEN Jing Nan, JIANG Yue, KWAN Kin Ming, PENG Cheng, JIAO Rui, ZUO Yuan Yuan, HUANG Yu, CHEN Zhen Yu. Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet[J]. Biomedical and Environmental Sciences, 2012, 25(4): 392-398. doi: 10.3967/0895-3988.2012.04.003