Increase of TNFα-stimulated Osteoarthritic Chondrocytes Apoptosis and Decrease of Matrix Metalloproteinases 9 by NF-κB Inhibition
- WANG Yan,
- LI De Ling,
- ZHANG Xin Bo,
- DUAN Yuan Hui,
- WU Zhi Hong,
- HAO Dong Sheng,
- CHEN Bao Sheng,
- QIU Gui Xing
-
Department of general surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
-
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China;Department of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100009, China
-
Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100009, China
-
Department of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100009, China
-
-
Key words:
- Chondrocytes /
- Gelatinase /
- Apoptosis /
- NF-κB /
- Tumor necrosis factor α
-
[1] Jun Ge, Fei Liu, Hongyun Nie, Yuan Yue, Kaige Liu, Haiguan Lin, Hao Li, Tao Zhang, Hongfeng Yan, Bingxin Xu, Hongwei Sun, Jianwu Yang, Shaoyan Si, Jinlian Zhou, Yan Cui. Simulated Microgravity can Promote the Apoptosis and Change Inflammatory State of Kupffer Cells . Biomedical and Environmental Sciences, 2024, 37(10): 1117-1127. doi: 10.3967/bes2024.141 [2] LI Min, DONG Xu Dong, LYU Qiu Bo, ZHANG Wei, HUANG Shuai, YANG Chun Xue, CUI Di, LAI Hui Ying. Phosphorylation of Cofilin-1 Enhances Paclitaxel Resistance of Epithelial Ovarian Cancer Cells by Inhibiting Apoptosis . Biomedical and Environmental Sciences, 2021, 34(6): 465-477. doi: 10.3967/bes2021.063 [3] ZHANG Tao, ZHENG Yu Dan, JIAO Man, ZHI Ye, XU Shen Ya, ZHU Piao Yu, ZHAO Xin Yuan, WU Qi Yun. Nuclear Factor-κB Signaling Mediates Antimony-induced Astrocyte Activation . Biomedical and Environmental Sciences, 2021, 34(1): 29-39. doi: 10.3967/bes2021.005 [4] XU Yong Jie, HU Mei Ling, ZHOU Liang Hui, WANG Qi, ZHANG Xi Quan, LUO Qing Bin. Effect of HSPB9 on Apoptosis of DF-1 Cells . Biomedical and Environmental Sciences, 2019, 32(2): 107-120. doi: 10.3967/bes2019.015 [5] ZHAO Li, LI Jing, HAO Yan Hui, GAO Ya Bing, WANG Shui Ming, ZHANG Jing, DONG Ji, ZHOU Hong Mei, LIU Shu Chen, PENG Rui Yun. Microwave-induced Apoptosis and Cytotoxicity of NK Cells through ERK1/2 Signaling . Biomedical and Environmental Sciences, 2017, 30(5): 323-332. doi: 10.3967/bes2017.043 [6] YAO Fang, ZHANG Jia Yan, XIAO Xiang, DONG Ying, ZHOU Xing Hua. Antitumor Activities and Apoptosis-regulated Mechanisms of Fermented Barley Extract in the Transplantation Tumor Model of Human HT-29 Cells in Nude Mice . Biomedical and Environmental Sciences, 2017, 30(1): 10-21. doi: 10.3967/bes2017.002 [7] GAO Hui, LI Ling Yu, ZHANG Man, ZHANG Quan. Inactivated Sendai Virus Induces Apoptosis Mediated by Reactive Oxygen Species in Murine Melanoma Cells . Biomedical and Environmental Sciences, 2016, 29(12): 877-884. doi: 10.3967/bes2016.117 [8] YUAN Zhun, YING Xian Ping, ZHONG Wei Jian, TIAN Shi Min, WANG Yu, JIA Yong Rui, CHEN Wen, FU Juan Ling, ZHAO Peng, ZHOU Zong Can. Autophagy Attenuates MnCl2-induced Apoptosis in Human Bronchial Epithelial Cells . Biomedical and Environmental Sciences, 2016, 29(7): 494-504. doi: 10.3967/bes2016.065 [9] TAO Yong Kang, YU Pu Lin, BAI Yong Ping, YAN Sheng Tao, ZHAO Shui Ping, ZHANG Guo Qiang. Role of PERK/eIF2α/CHOP Endoplasmic Reticulum Stress Pathway in Oxidized Low-density Lipoprotein Mediated Induction of Endothelial Apoptosis . Biomedical and Environmental Sciences, 2016, 29(12): 868-876. doi: 10.3967/bes2016.116 [10] ZHANG Jia Yan, XIAO Xiang, DONG Ying, WU Jing, ZHOU Xing Hua. Antitumor Activities and Apoptosis-regulated Mechanisms of Fermented Wheat Germ Extract in the Transplantation Tumor Model of Human HT-29 Cells in Nude Mice . Biomedical and Environmental Sciences, 2015, 28(10): 718-727. doi: 10.3967/bes2015.102 [11] ZHAO Ya Ning, LI Qiang. Adenovirus Mediated BIMS Transfer Induces Growth Supression and Apoptosis in Raji Lymphoma Cells . Biomedical and Environmental Sciences, 2014, 27(9): 655-664. doi: 10.3967/bes2014.101 [12] CUI Bo, WU Ming Quan, ZHU Li Xing, SHE Xiao Jun, MA Qiang, LIU Hong Tao. Effect of Chronic Noise Exposure on Expression of N-Methyl-D-Aspartic Acid Receptor 2B and Tau Phosphorylation in Hippocampus of Rats . Biomedical and Environmental Sciences, 2013, 26(3): 163-168. doi: 10.3967/0895-3988.2013.03.002 [13] WANG Jing, LV XiaoWen, SHI JiePing, HU XiaoSong, DU YuGuo. Troglitazone Induced Apoptosis via PPARy Activated POX-induced ROS Formation in HT29 Cells . Biomedical and Environmental Sciences, 2011, 24(4): 391-399. doi: 10.3967/0895-3988.2011.04.010 [14] RUN AN, JIE MENG, QI SHI, XIAO-XIA DAI, JING-HONG CHEN, YAN-JUN LEI, BING SHAN, CHEN GAO, YONG-LIE CHU, XIAO-PING DONG. Expressions of Nucleoside Diphosphate Kinase (nm23)in Tumor Tissues are Related with Metastasis and Length of Survival of Patients with Hepatocellular Carcinoma . Biomedical and Environmental Sciences, 2010, 23(4): 267-272. [15] GUANG-YU LI, BIN FAN, YONG-CHEN ZHENG. Calcium Overload Is A Critical Step in Programmed Necrosis of ARPE-19 Cells Induced by High-Concentration H2O2 . Biomedical and Environmental Sciences, 2010, 23(5): 371-377. [16] A-JING YANG, WEI-WEI SHI, YONG LI, ZHEN WANG, RONG-GUANG SHAO, DIAN-DONG LI, QI-YANG HE. Role of Prosurvival Molecules in the Action of Lidamycin toward Human Tumor Cells . Biomedical and Environmental Sciences, 2009, 22(3): 244-252. [17] SHOU-LIANG GONG, LI-HUA DONG, GUANG-WEI LIU, PING-SHENG GONG, WEN-TIAN LU, HONG-GUANG ZHAO, XIAO-JING JIA, YONG ZHAO. Effects of Corticosterone,cAMP,cGMP,Ca2+,and Protein Kinase C on Apoptosis of Mouse Thymocytes Induced by X-ray Irradiation . Biomedical and Environmental Sciences, 2008, 21(2): 167-172. [18] RI-AN YU, TAO XIA, AI-GUO WANG, XUE-MIN CHEN. Effects of Selenium and Zinc on Renal Oxidative Stress and Apoptosis Induced by Fluoride in Rats . Biomedical and Environmental Sciences, 2006, 19(6): 439-444. [19] SU-MIN LI, XIAO-MING WANG, JIN QIU, QIN SI, HENG-YI GUO, REN-YU SUN, QI-XIA WU. Inhibitory Effects of Alpha-zearalenol on Angiotensin II-Induced Integrin β3 mRNA via Suppression of Nuclear Factor-κB . Biomedical and Environmental Sciences, 2005, 18(5): 314-320. [20] AI-GUO WANG, TAO Xia, QI-LONG CHU, Ming Zhang, FANG LIU, XUE-MIN CHEN, KE-DI YANG. Effects of Fluoride on Lipid Peroxidation, DNA Damage and Apoptosis in Human Embryo Hepatocytes . Biomedical and Environmental Sciences, 2004, 17(2): 217-222. -
点击查看大图
计量
- 文章访问数: 1613
- HTML全文浏览量: 442
- PDF下载量: 47
- 被引次数: 0
出版历程
- 刊出日期: 2013-04-20
下载:
Quick Links