Effects of Low Concentrations of Di-(2-ethylhexyl) and Mono-(2-ethylhexyl) Phthalate on Steroidogenesis Pathways and Apoptosis in the Murine Leydig Tumor Cell Line MLTC-1
-
Department of 0ccupational and Environmental Health, School of Public Health, Tianjin Medical University, Tianjin 300070, China
-
Tianjin Central Hospital of Gynecology and 0bstetrics, Tianjin 300100, China
Funds: the National Natural Science Foundation of China (81273028)
-
-
[1] XU Xiao Mei, LI Xiao Lu, HU Die, CAI Xiao Yue, LI Qi Meng, ZHENG Yuan Zhuo, CAI Yang, QI Yin Yin, XU Tao, ZHAO Ling Li, NING Xia. Identification of Key Blood Biomarkers Linking Di (2-ethylhexyl) Phthalate and Autoimmune Diseases in Adolescents Mice . Biomedical and Environmental Sciences, 2024, 37(5): 521-525. doi: 10.3967/bes2024.057 [2] LI Mo Juan, XIONG Dan, WANG Shuai, HUANG Hao. Tra2β Enhances Cell Proliferation by Inducing the Expression of Transcription Factor SP1 in Cervical Cancer . Biomedical and Environmental Sciences, 2023, 36(2): 146-159. doi: 10.3967/bes2023.018 [3] LIU Miao Qing, CHEN Hai Qiong, DAI Hai Peng, LI Jing Jing, TIAN Fu Hong, WANG Yi Yan, CHEN Cong De, LI Xiao Heng, LI Jun Wei, LI Zhong Rong, GE Ren Shan. Bis (2-butoxyethyl) Phthalate Delays Puberty Onset by Increasing Oxidative Stress and Apoptosis in Leydig Cells in Rats . Biomedical and Environmental Sciences, 2023, 36(1): 60-75. doi: 10.3967/bes2023.006 [4] XU Qi, ZHANG Bo, LI Xu, YE Jia Ming, HUO Chuan Yi, YIN Jian Li, ZHANG Ru Xuan, ZHAO Wei Sen, QI Wen, YE Lin. Mono-2-ethylhexyl Phthalate Promotes Migration and Invasion by Regulating the Epithelial-Mesenchymal Transition in SH-SY5Y Cells . Biomedical and Environmental Sciences, 2022, 35(3): 276-281. doi: 10.3967/bes2022.039 [5] DONG Xin Wen, WU Wei Dong, YAO San Qiao, ZHANG Yun Bo, WANG Cheng, WU Hao Yu, NA Xiao Lin. Long-term Di-(2-ethylhexyl) phthalate Exposure Disturbs the Lipid Metabolism Profiles and Hepatic Enzymes in Male Rats: A UPLC-MS-based Serum Metabolomics Analysis . Biomedical and Environmental Sciences, 2021, 34(11): 920-925. doi: 10.3967/bes2021.127 [6] DONG Xin Wen, YAO San Qiao, WU Hao Yu, ZHANG Yun Bo, WANG Cheng, NA Xiao Lin, WU Wei Dong. Urine Metabonomic Analysis of Interventions Effect of Soy Isoflavones on Rats Exposed to Di-(2-ethylhexyl) Phthalate . Biomedical and Environmental Sciences, 2020, 33(2): 77-88. doi: 10.3967/bes2020.012 [7] QIN Xiao Yun, MA Quan, XU Xin Yun, TAN Qin, ZHENG Kai, WANG Bing Yu. Di-2-Ethylhexyl Phthalate Induces Ovarian Toxicity and Alters Protein Expression of Hormone-regulated Receptors in Rats . Biomedical and Environmental Sciences, 2019, 32(7): 546-549. doi: 10.3967/bes2019.071 [8] ZHANG Yue Zhu, ZHANG Zhao Ming, ZHOU Li Ting, ZHU Jian, ZHANG Xiao Han, QI Wen, DING Shuang, XU Qi, HAN Xu, ZHAO Ya Ming, SONG Xin Yue, ZHAO Tian Yang, YE Lin. Di (2-ethylhexyl) phthalate Disorders Lipid Metabolism via TYK2/STAT1 and Autophagy in Rats . Biomedical and Environmental Sciences, 2019, 32(6): 406-418. doi: 10.3967/bes2019.055 [9] Yang Yun-jung, Park Moon-seo, Lee Eui-Jin, Hong Yeon-pyo. The Development of Metabolic Derangement in Male Offspring after Perinatal Exposure to Di-(2-Ethylhexyl) Phthalate . Biomedical and Environmental Sciences, 2018, 31(7): 531-534. doi: 10.3967/bes2018.071 [10] ZHAO Li, LI Jing, HAO Yan Hui, GAO Ya Bing, WANG Shui Ming, ZHANG Jing, DONG Ji, ZHOU Hong Mei, LIU Shu Chen, PENG Rui Yun. Microwave-induced Apoptosis and Cytotoxicity of NK Cells through ERK1/2 Signaling . Biomedical and Environmental Sciences, 2017, 30(5): 323-332. doi: 10.3967/bes2017.043 [11] WU Jian Hui, CHEN Jiao, WANG Yong, XIA Bin, WANG Rong, ZHAO Yan, WANG Qin Xia, SONG Qi, YAO Shun Heng, ZHANG Yun Hui, SUN Zu Yue. Effect of Mono-2-ethyhexyl Phthalate on DNA Methylation in Human Prostate Cancer LNCaP Cells . Biomedical and Environmental Sciences, 2017, 30(9): 641-648. doi: 10.3967/bes2017.085 [12] TAO Yong Kang, YU Pu Lin, BAI Yong Ping, YAN Sheng Tao, ZHAO Shui Ping, ZHANG Guo Qiang. Role of PERK/eIF2α/CHOP Endoplasmic Reticulum Stress Pathway in Oxidized Low-density Lipoprotein Mediated Induction of Endothelial Apoptosis . Biomedical and Environmental Sciences, 2016, 29(12): 868-876. doi: 10.3967/bes2016.116 [13] XIANG Ruo Lan, MEIMei, SU Yun Chao, LI Li, WANG Jin Yu, WU Li Ling. Visfatin Protects Rat Pancreatic β-cells against IFN-γ-Induced Apoptosis through AMPK and ERK1/2 Signaling Pathways . Biomedical and Environmental Sciences, 2015, 28(3): 169-177. doi: 10.3967/bes2015.023 [14] ZUO Hao Xiao, LI Jin Quan, HAN Bing, KE Chen Juan, LIU Xu Dong, ZHANG Yu Chao, LI Li, YANG Xu. Di-(n-butyl)-phthalate-induced Oxidative Stress and Depression-like Behavior in Mice with or without Ovalbumin Immunization . Biomedical and Environmental Sciences, 2014, 27(4): 268-280. doi: 10.3967/bes2014.001 [15] LU Jie, ZHANG Jing, WANG Zhu Tian, FAN Yong Xiang. An Estimation of the Daily Intake of Di (2-ethlhexyl) Phthalate (DEHP) among Workers in Flavoring Factories . Biomedical and Environmental Sciences, 2014, 27(6): 419-425. doi: 10.3967/bes2014.071 [16] GAO Xue Juan, FENG Jun Xia, ZHU Sen, LIU Xiao Hui, TARDIEUX Isabelle, LIU Lang Xia. Protein Phosphatase 2C of Toxoplasma Gondii Interacts with Human SSRP1 and Negatively Regulates Cell Apoptosis . Biomedical and Environmental Sciences, 2014, 27(11): 883-893. doi: 10.3967/bes2014.130 [17] YUAN Xuan, ZHANG Bo, GAN Lu, WANG Zhen Hua, YU Ba Cui, LIU Liang Liang, ZHENG Qiu Sheng, WANG Zhi Ping. Involvement of the Mitochondrion-dependent and the Endoplasmic Reticulum Stress-signaling Pathways in Isoliquiritigenin-induced Apoptosis of HeLa Cell . Biomedical and Environmental Sciences, 2013, 26(4): 268-276. doi: 10.3967/0895-3988.2013.04.005 [18] MENG YE, BING-CI LIU, XIANG-LIN SHI, BAO-RONG YOU, HONG-JU DU, XIAO-WEI JIA, FU-HAI SHEN. Different Patterns of Cyclin D1/CDK4-E2F-1/4 Pathways in Human Embryo Lung Fibroblasts Treated by Benzo[a]pyrene at Different Doses1 . Biomedical and Environmental Sciences, 2008, 21(1): 30-36. [19] LEI JIA, LI-ZHE AN. Effects of the Extract of Ammopiptanthus mongolicus cheng f. (JA1) on Induction of Apoptosis of HepG2 in vitro and Its Molecular Mechanisms . Biomedical and Environmental Sciences, 2006, 19(2): 118-123. [20] WU XIANG-DONG, YANG JIAN-MING, WU XIAO-YUN, DING XUN-CHENG, PANG BING, JIANG XUE-ZHI, JI ZAI-SI, SHIN KAZUO. The effects of 2-Bromopropane on Viability and Testosterone Production Ability of Rat Leydig Cells in Primary Culture . Biomedical and Environmental Sciences, 1999, 12(1): 43-49. -

计量
- 文章访问数: 1675
- HTML全文浏览量: 498
- PDF下载量: 63
- 被引次数: 0
出版历程
- 刊出日期: 2013-12-20